INO80D Activators
INO80 Complex Subunit D, often abbreviated as INO80D, is a protein encoded by the INO80D gene in humans. This protein is a crucial component of the INO80 chromatin remodeling complex, a multi-protein assembly that plays key roles in several DNA-related processes.Chromatin remodeling complexes like INO80 help regulate the accessibility of DNA to various proteins involved in processes such as transcription, replication, and DNA repair. They achieve this by altering the structure of chromatin, the substance within chromosomes that is composed of DNA and protein, specifically histones.
INO80D, as a component of the INO80 complex, contributes to the stability and assembly of this complex. It interacts with other subunits within the complex, aiding it in binding to specific regions of chromatin. This enables the INO80 complex to carry out its role in chromatin remodeling, thereby facilitating the aforementioned DNA processes.Mutations in the INO80D gene could potentially disrupt the function or the formation of the INO80 complex, thereby impacting DNA repair, transcription, and replication. However, defects in other components of the INO80 complex have been implicated in certain diseases, including cancer, suggesting that INO80D could also potentially contribute to disease if its function is compromised.INO80D is expressed in a variety of human tissues, reflecting its broad role in DNA processes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $133.00 $275.00 | 37 | |
Vorinostat, another histone deacetylase inhibitor, might indirectly impact INO80D activity. | ||||||
Nicotinamide | 98-92-0 | sc-208096 sc-208096A sc-208096B sc-208096C | 100 g 250 g 1 kg 5 kg | $44.00 $66.00 $204.00 $831.00 | 6 | |
As an inhibitor of sirtuins, nicotinamide can affect chromatin structure and potentially INO80D function. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $87.00 | 9 | |
Valproic acid, a histone deacetylase inhibitor, could have an indirect effect on INO80D. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin affects various signaling pathways and might influence chromatin remodeling and INO80D. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol influences gene expression and chromatin structure, potentially impacting INO80D. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Genistein, a phytoestrogen, can modulate chromatin and might affect INO80D. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
Sulforaphane may influence histone acetylation and could indirectly impact INO80D. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG can modulate epigenetic mechanisms, potentially influencing INO80D. | ||||||
3-Hydroxybutyric acid | 300-85-6 | sc-231749 sc-231749A sc-231749B | 1 g 5 g 25 g | $71.00 $122.00 $449.00 | ||
This ketone body influences histone acetylation and could impact INO80D. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
Zinc plays a role in DNA repair and transcription, and could indirectly influence INO80D. | ||||||