Date published: 2026-4-1

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IL-29 Inhibitors

Chemical Class Description: The class of IL-29 inhibitors includes a range of compounds that indirectly modulate the activity of IL-29 by targeting various signaling pathways and cellular processes. These compounds do not interact directly with IL-29 but influence the cellular environment and mechanisms in which IL-29 operates. JAK inhibitors like JAK Inhibitor I, Ruxolitinib, and Tofacitinib target the JAK-STAT pathway, which is crucial for the signal transduction of IL-29. STAT inhibitors such as Stattic, WP1066, and S3I-201 disrupt STAT3 phosphorylation and activity, key components of IL-29 signaling.

AG490, as a tyrosine kinase inhibitor, and Sorafenib, as a broad kinase inhibitor, might impact signaling pathways related to IL-29's immune-modulating functions. Curcumin, with its wide-ranging effects on cellular signaling, and BAY 11-7082, an NF-κB inhibitor, represent different mechanisms of potentially modulating IL-29's activities. LY294002, a PI3K inhibitor, and SB203580, a p38 MAPK inhibitor, further illustrate diverse approaches to influencing signaling pathways associated with IL-29.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Stat3 inhibitor V, stattic

19983-44-9sc-202818
sc-202818A
sc-202818B
sc-202818C
sc-202818D
sc-202818E
sc-202818F
25 mg
100 mg
250 mg
500 mg
1 g
2.5 g
5 g
$130.00
$196.00
$274.00
$512.00
$731.00
$1408.00
$2091.00
114
(3)

Inhibits STAT3, a key component in the JAK-STAT signaling pathway influenced by IL-29.

Ruxolitinib

941678-49-5sc-364729
sc-364729A
sc-364729A-CW
5 mg
25 mg
25 mg
$251.00
$500.00
$547.00
16
(1)

JAK inhibitor, might modulate the JAK-STAT pathway involved in IL-29 signaling.

Stat3 Inhibitor III, WP1066

857064-38-1sc-203282
10 mg
$132.00
72
(1)

Inhibits STAT3 phosphorylation, potentially affecting STAT3-mediated signaling by IL-29.

Tyrphostin B42

133550-30-8sc-3556
5 mg
$26.00
4
(1)

Tyrosine kinase inhibitor, might impact JAK-STAT signaling in IL-29 pathways.

BAY 11-7082

19542-67-7sc-200615B
sc-200615
sc-200615A
5 mg
10 mg
50 mg
$62.00
$85.00
$356.00
155
(1)

NF-κB inhibitor, could influence downstream effects of IL-29 signaling.

Stat3 Inhibitor VI, S3I-201

501919-59-1sc-204304
10 mg
$151.00
104
(1)

STAT3 inhibitor, potentially disrupting STAT3-dependent signaling in IL-29 pathways.

Sorafenib

284461-73-0sc-220125
sc-220125A
sc-220125B
5 mg
50 mg
500 mg
$57.00
$100.00
$250.00
129
(3)

Kinase inhibitor, might modulate pathways involved in IL-29 signaling.