Date published: 2026-4-12

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IL-1R Antibodies

Santa Cruz Biotechnology features a diverse variety of IL-1R monoclonal antibodies for advanced research in immunology and cell signaling. IL-1R Antibodies are compatible with multiple techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Interleukin-1 receptor (IL-1R) plays a crucial role in mediating the effects of interleukin-1, a key pro-inflammatory cytokine involved in immune responses. The activation of IL-1R triggers a cascade of signaling pathways that regulate inflammation, cell proliferation, and apoptosis, making it essential for maintaining homeostasis and responding to infection. Dysregulation of IL-1R signaling has been implicated in various diseases, including autoimmune disorders and cancer, highlighting the importance of studying this receptor. IL-1R monoclonal antibodies enable precise detection and analysis of receptor expression, localization, and activation states. Studying IL-1R signaling pathways helps advance understanding of inflammatory processes and disease mechanisms. IL-1R research using Santa Cruz Biotechnology monoclonal antibodies contributes to developing new therapeutic strategies for inflammatory and autoimmune conditions.

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IL-1R Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

IL-1RAcP Antibody (D-5)

sc-376872mouse IgG2b κ221-348 (h)WB, IP, IF, IHC(P), ELISAm, r, h
2
(5)

IL-1RI Antibody (H-8)

sc-393998mouse IgG1 κ539-563 (m)WB, IP, IF, ELISAm, r, h
33
(5)

IL-1RI Antibody (102)

sc-66054mouse IgG2a(h)IF, IHC(P)h

new

(1)

IL-1RII Antibody (G-5)

sc-376247mouse IgG1 κ257-327 (h)WB, IP, IF, ELISAh
3
(1)

IL-1RII Antibody (6G5)

sc-52678mouse IgG2aN/AWB, IP, ELISAh
2
(1)

IL-1R CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

IL-1RAcP CRISPR/Cas9 KO Plasmid (h)

sc-402026hGene KnockoutGFP0
(0)

IL-1RAcP HDR Plasmid (h)

sc-402026-HDRhHomology Directed RepairPuromycin0
(0)

IL-1RAcP Double Nickase Plasmid (h)

sc-402026-NIChGene KnockoutPuromycin0
(0)

IL-1RAcP Double Nickase Plasmid (h2)

sc-402026-NIC-2hGene KnockoutPuromycin0
(0)

IL-1RAcP CRISPR/Cas9 KO Plasmid (m)

sc-421101mGene KnockoutGFP0
(0)

IL-1RI CRISPR/Cas9 KO Plasmid (h)

sc-401144hGene KnockoutGFP0
(0)

IL-1RI HDR Plasmid (h)

sc-401144-HDRhHomology Directed RepairPuromycin0
(0)

IL-1RI Double Nickase Plasmid (h)

sc-401144-NIChGene KnockoutPuromycin0
(0)

IL-1RI Double Nickase Plasmid (h2)

sc-401144-NIC-2hGene KnockoutPuromycin0
(0)

IL-1RI CRISPR/Cas9 KO Plasmid (m)

sc-421098mGene KnockoutGFP0
(0)

IL-1RI HDR Plasmid (m)

sc-421098-HDRmHomology Directed RepairPuromycin0
(0)

IL-1RI Double Nickase Plasmid (m)

sc-421098-NICmGene KnockoutPuromycin0
(0)

IL-1RI Double Nickase Plasmid (m2)

sc-421098-NIC-2mGene KnockoutPuromycin0
(0)

IL-1RII CRISPR/Cas9 KO Plasmid (m)

sc-421099mGene KnockoutGFP0
(0)

IL-1R CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

IL-1RAcP CRISPR Activation Plasmid (h)

sc-402026-ACThGene ActivationPuro, Blast, Hygro0
(0)

IL-1RII CRISPR Activation Plasmid (m)

sc-421099-ACTmGene ActivationPuro, Blast, Hygro0
(0)

IL-1R siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

IL-1RAcP siRNA (h)

sc-60831hGene SilencingN/A0
(0)

IL-1RAcP shRNA Plasmid (h)

sc-60831-SHhGene SilencingPuromycin0
(0)

IL-1RAcP shRNA (h) Lentiviral Particles

sc-60831-VhGene SilencingPuromycin0
(0)

IL-1RAcP siRNA (m)

sc-60832mGene SilencingN/A0
(0)

IL-1RAcP shRNA Plasmid (m)

sc-60832-SHmGene SilencingPuromycin0
(0)

IL-1RAcP shRNA (m) Lentiviral Particles

sc-60832-VmGene SilencingPuromycin0
(0)

IL-1RI siRNA (h)

sc-35651hGene SilencingN/A
3
(0)

IL-1RI shRNA Plasmid (h)

sc-35651-SHhGene SilencingPuromycin
3
(0)

IL-1RI shRNA (h) Lentiviral Particles

sc-35651-VhGene SilencingPuromycin
3
(0)

IL-1RI siRNA (m)

sc-35652mGene SilencingN/A
1
(0)

IL-1RI shRNA Plasmid (m)

sc-35652-SHmGene SilencingPuromycin
1
(0)

IL-1RI shRNA (m) Lentiviral Particles

sc-35652-VmGene SilencingPuromycin
1
(0)

IL-1RII siRNA (h)

sc-72042hGene SilencingN/A0
(0)

IL-1RII shRNA Plasmid (h)

sc-72042-SHhGene SilencingPuromycin0
(0)

IL-1RII shRNA (h) Lentiviral Particles

sc-72042-VhGene SilencingPuromycin0
(0)

IL-1RII siRNA (m)

sc-72043mGene SilencingN/A0
(0)

IL-1RII shRNA Plasmid (m)

sc-72043-SHmGene SilencingPuromycin0
(0)

IL-1RII shRNA (m) Lentiviral Particles

sc-72043-VmGene SilencingPuromycin0
(0)

IL-1R8 siRNA (h)

sc-91336hGene SilencingN/A0
(0)

IL-1R8 shRNA Plasmid (h)

sc-91336-SHhGene SilencingPuromycin0
(0)

IL-1R8 shRNA (h) Lentiviral Particles

sc-91336-VhGene SilencingPuromycin0
(0)

IL-1R9 siRNA (h)

sc-90992hGene SilencingN/A0
(0)

IL-1R9 shRNA Plasmid (h)

sc-90992-SHhGene SilencingPuromycin0
(0)

IL-1R9 shRNA (h) Lentiviral Particles

sc-90992-VhGene SilencingPuromycin0
(0)