Date published: 2025-12-21

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IL-17REL 활성제

IL-17REL is a member of the interleukin-17 (IL-17) family of cytokines, which are known for their role in inflammatory processes and host defense against infections. This family includes several members, such as IL-17A through IL-17F, each encoded by different genes and exhibiting distinct but related biological functions. IL-17 cytokines are predominantly produced by a unique subset of T cells known as Th17 cells, although other cell types like γδ T cells and innate immune cells can also produce them under certain conditions.

IL-17REL is the least characterized member of the IL-17 family and shares sequence homology with other IL-17 family cytokines, suggesting it may have similar biological activities. The "REL" suffix denotes its relationship to the other IL-17 family members, but also its distinctiveness, as it is not as extensively studied. Due to the naming conventions of cytokines, the "REL" might imply a relative or a homolog to the better-characterized IL-17 cytokines, particularly IL-17A and IL-17F, which are the most studied and are known to mediate pro-inflammatory responses.While the exact function of IL-17REL is not well-defined, it is presumed to be involved in immune system signaling pathways, contributing to the orchestration of immune responses. Like other IL-17 cytokines, it may play a role in inducing the production of other pro-inflammatory molecules, such as chemokines and cytokines, which recruit and activate other immune cells to the site of infection or inflammation.

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제품명CAS #카탈로그 번호 수량가격引用RATING

PMA

16561-29-8sc-3576
sc-3576A
sc-3576B
sc-3576C
sc-3576D
1 mg
5 mg
10 mg
25 mg
100 mg
$40.00
$129.00
$210.00
$490.00
$929.00
119
(6)

PMA는 단백질 키나아제 C를 활성화하여 IL-17REL의 발현을 향상시킬 수 있는 전사인자인 NF-κB의 활성화를 유도할 수 있습니다.

Lipopolysaccharide, E. coli O55:B5

93572-42-0sc-221855
sc-221855A
sc-221855B
sc-221855C
10 mg
25 mg
100 mg
500 mg
$96.00
$166.00
$459.00
$1615.00
12
(2)

LPS는 TLR4에 결합하여 NF-κB를 활성화하는 신호 캐스케이드를 시작하여 잠재적으로 면역 세포에서 IL-17REL 발현을 증가시킵니다.

R-848

144875-48-9sc-203231
sc-203231A
sc-203231B
sc-203231C
5 mg
25 mg
100 mg
500 mg
$100.00
$300.00
$500.00
$1528.00
12
(1)

레시퀴모드는 TLR7과 TLR8을 활성화하여 염증성 사이토카인을 유도하고 IL-17REL을 상향 조절할 수 있습니다.

Imiquimod

99011-02-6sc-200385
sc-200385A
100 mg
500 mg
$66.00
$278.00
6
(1)

TLR7 작용제인 이미퀴모드는 선천성 면역 체계를 자극할 수 있으며 IL-17REL의 발현을 유도할 수 있습니다.

Dexamethasone Sodium Phosphate

2392-39-4sc-204715
sc-204715A
100 mg
500 mg
$54.00
$155.00
7
(1)

이러한 TLR9 작용제는 NF-κB의 활성화를 촉진하여 IL-17REL 발현을 증가시킬 수 있습니다.

Pam3Cys-Ser-(Lys)4, Hydrochloride

112208-00-1sc-507471
2 mg
$550.00
(0)

이 TLR1/2 작용제는 신호 캐스케이드를 유발하여 NF-κB 활성화와 잠재적인 IL-17REL 상향 조절을 유발할 수 있습니다.

Polyinosinic-polycytidylic acid potassium salt

31852-29-6sc-202767
5 mg
$194.00
(1)

TLR3 작용제로서 IRF3와 NF-κB를 활성화하여 IL-17REL 발현을 향상시킬 수 있습니다.