Date published: 2025-10-25

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IL-17REL阻害剤

IL-17REL inhibitors are a specialized class of chemical compounds designed to specifically target and inhibit the activity of IL-17REL, a member of the interleukin-17 receptor family. IL-17REL, or Interleukin-17 Receptor E-like, is a protein that plays a role in the complex signaling pathways involved in immune responses. While its exact functions are still under investigation, IL-17REL is believed to be involved in modulating immune responses, particularly those related to inflammatory processes. By inhibiting IL-17REL, researchers aim to dissect its specific role within the broader context of immune system regulation and to understand how it interacts with other members of the IL-17 receptor family, which are known to be critical in host defense mechanisms.

The study of IL-17REL inhibitors is important for expanding our knowledge of the intricate network of cytokine signaling that underpins immune system function. These inhibitors are used in various experimental settings to block the activity of IL-17REL and observe the resulting changes in cellular behavior and immune responses. This approach allows scientists to identify the pathways and molecular interactions in which IL-17REL is involved, providing insights into how this receptor contributes to the regulation of inflammation and immune homeostasis. Additionally, understanding the specific actions of IL-17REL through the use of inhibitors can shed light on its potential role in pathological conditions where immune dysregulation is a factor. By studying IL-17REL inhibitors, researchers can gain a deeper understanding of the receptor's function, which may have broader implications for understanding the immune system's balance and how it responds to various stimuli.

関連項目

製品名CAS #カタログ #数量価格引用文献レーティング

Apilimod

541550-19-0sc-480051
sc-480051A
100 mg
1 g
$420.00
$2600.00
5
(0)

アピリモドは選択的PIKfyve阻害剤であり、エンドソームの輸送を変化させることでインターロイキン-17(IL-17)受容体ファミリー軸に結びついた細胞内シグナル伝達経路を混乱させ、インターロイキン-17(IL-17)受容体ファミリー媒介シグナル伝達を減弱させることができる。

Wortmannin

19545-26-7sc-3505
sc-3505A
sc-3505B
1 mg
5 mg
20 mg
$66.00
$219.00
$417.00
97
(3)

WortmanninはPI3K阻害剤であり、IL-17R経路と交差するPI3K-Akt経路においてその役割を通じて、間接的にインターロイキン-17(IL-17)受容体ファミリーシグナル伝達を減少させることができる。