Date published: 2026-4-5

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IL-1 β Antibodies

Santa Cruz Biotechnology delivers a wide array of IL-1 β monoclonal antibodies for research focused on understanding this critical cytokine. IL-1 β monoclonal antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). IL-1 β is a key pro-inflammatory cytokine involved in the regulation of immune and inflammatory responses. IL-1 β plays a significant role in various physiological processes, including cell proliferation, differentiation, and apoptosis. Dysregulation of IL-1 β has been implicated in numerous diseases, including autoimmune disorders, chronic inflammatory conditions, and cancer, making it a vital target for therapeutic intervention. IL-1 β research continues to reveal new insights into inflammatory pathways and disease mechanisms. Understanding IL-1 β signaling pathways helps identify potential therapeutic targets for inflammatory conditions. IL-1 β monoclonal antibodies enable precise detection and analysis of this important cytokine. Santa Cruz Biotechnology monoclonal antibodies support researchers worldwide in advancing our understanding of IL-1 β's role in health and disease.

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IL-1 β Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

IL-1 beta/IL1B Antibody (F-5)

sc-515598mouse IgG2a κ238-268 (r)WB, IP, IF, ELISAm, r, h
30
(2)

IL-1 beta/IL1B Antibody (B122)

sc-12742Armenian Hamster IgG(m)WB, IP, ELISAm, r, h, hamster
166
(32)

IL-1 beta/IL1B Antibody (E7-2-hIL1β)

sc-32294mouse IgG2b κ(h)WB, IP, IF, IHC(P)h
133
(34)

IL-1 beta/IL1B Antibody (11E5)

sc-52012mouse IgG1(h)WB, IP, IF, IHC(P)m, r, h
160
(16)

IL-1 beta/IL1B Antibody (H-8)

sc-515786mouse IgG1 κ117-269 (h)WB, IP, IF, ELISAh

new

(0)

IL-1 beta/IL1B Antibody (E-12)

sc-515787mouse IgG1 κ117-269 (h)WB, IP, IF, ELISAh

new

(0)

IL-1 beta/IL1B Antibody (AS57)

sc-52771mouse IgG2bFL (h)WB, IPh
3
(4)

IL-1 beta/IL1B Antibody (2H12)

sc-130323mouse IgG1(h)IF, IHC(P)h
7
(1)

IL-1 β CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

IL-1 beta/IL1B CRISPR/Cas9 KO Plasmid (h2)

sc-400078-KO-2hGene KnockoutGFP0
(0)

IL-1 beta/IL1B HDR Plasmid (h2)

sc-400078-HDR-2hHomology Directed RepairPuromycin0
(0)

IL-1 beta/IL1B Double Nickase Plasmid (h)

sc-400078-NIChGene KnockoutPuromycin0
(0)

IL-1 beta/IL1B Double Nickase Plasmid (h2)

sc-400078-NIC-2hGene KnockoutPuromycin0
(0)

IL-1 beta/IL1B CRISPR/Cas9 KO Plasmid (m)

sc-421097mGene KnockoutGFP
2
(0)

IL-1 beta/IL1B HDR Plasmid (m)

sc-421097-HDRmHomology Directed RepairPuromycin
2
(0)

IL-1 beta/IL1B Double Nickase Plasmid (m)

sc-421097-NICmGene KnockoutPuromycin
2
(0)

IL-1 beta/IL1B Double Nickase Plasmid (m2)

sc-421097-NIC-2mGene KnockoutPuromycin
2
(0)

IL-1 β CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

IL-1 beta/IL1B CRISPR Activation Plasmid (h)

sc-400078-ACThGene ActivationPuro, Blast, Hygro0
(0)

IL-1 beta/IL1B CRISPR Activation Plasmid (m)

sc-421097-ACTmGene ActivationPuro, Blast, Hygro
2
(0)

IL-1 beta/IL1B CRISPR Activation Plasmid (m2)

sc-421097-ACT-2mGene ActivationPuro, Blast, Hygro
2
(0)

IL-1 β siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

IL-1 beta/IL1B siRNA (h)

sc-39615hGene SilencingN/A
11
(1)

IL-1 beta/IL1B shRNA Plasmid (h)

sc-39615-SHhGene SilencingPuromycin
11
(1)

IL-1 beta/IL1B shRNA (h) Lentiviral Particles

sc-39615-VhGene SilencingPuromycin
11
(1)

IL-1 beta/IL1B siRNA (m)

sc-39616mGene SilencingN/A
3
(0)

IL-1 beta/IL1B shRNA Plasmid (m)

sc-39616-SHmGene SilencingPuromycin
3
(0)

IL-1 beta/IL1B shRNA (m) Lentiviral Particles

sc-39616-VmGene SilencingPuromycin
3
(0)

IL-1 beta/IL1B siRNA (r)

sc-45995rGene SilencingN/A
1
(0)

IL-1 beta/IL1B shRNA Plasmid (r)

sc-45995-SHrGene SilencingPuromycin
1
(0)

IL-1 beta/IL1B shRNA (r) Lentiviral Particles

sc-45995-VrGene SilencingPuromycin
1
(0)