IIp45 inhibitors are a class of chemical compounds that specifically target and inhibit the IIp45 protein, also known as MIIP (Migration and Invasion Inhibitory Protein). IIp45 is involved in regulating key cellular processes such as migration, invasion, and adhesion. It plays a significant role in controlling the dynamics of the cytoskeleton, which governs cell shape, movement, and interactions with the surrounding extracellular matrix. IIp45 influences cellular functions by modulating actin filament organization and interacting with proteins that control cellular adhesion. By inhibiting IIp45, these compounds interfere with its regulatory effects, leading to alterations in cell movement, structure, and how cells respond to external signals.
Research into IIp45 inhibitors is focused on understanding how this protein contributes to cellular motility and organization. By blocking the function of IIp45, scientists can explore its specific role in the mechanisms that enable cells to move through and interact with their environment. This can provide insights into how IIp45 affects processes such as tissue development, cell migration, and cellular invasion. Additionally, these inhibitors allow for the study of how IIp45 interacts with other molecular players involved in cytoskeletal organization, offering a deeper understanding of the signaling pathways and structural elements that underlie cellular movement. IIp45 inhibitors are valuable tools for dissecting the complex interactions between cytoskeletal proteins and cell signaling pathways, enabling researchers to gain a more detailed view of how cells regulate their shape, motility, and interactions with the surrounding matrix.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $41.00 $74.00 $221.00 $247.00 $738.00 $1220.00 | 39 | |
Stabilizes microtubules and can disrupt cell division, potentially affecting MIIP-related pathways. | ||||||
Vinblastine | 865-21-4 | sc-491749 sc-491749A sc-491749B sc-491749C sc-491749D | 10 mg 50 mg 100 mg 500 mg 1 g | $102.00 $235.00 $459.00 $1749.00 $2958.00 | 4 | |
Inhibits microtubule formation, which can alter cellular processes related to MIIP. | ||||||
Colchicine | 64-86-8 | sc-203005 sc-203005A sc-203005B sc-203005C sc-203005D sc-203005E | 1 g 5 g 50 g 100 g 500 g 1 kg | $100.00 $321.00 $2289.00 $4484.00 $18207.00 $34749.00 | 3 | |
Binds to tubulin, affecting microtubule polymerization, indirectly influencing MIIP functions. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $59.00 $85.00 $143.00 $247.00 | 38 | |
Destabilizes microtubules and may alter cell migration and invasion, connected to MIIP activity. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
ROCK inhibitor, which might modify cell shape and motility, processes associated with MIIP. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
MEK inhibitor, can affect MAPK/ERK pathway, potentially modulating MIIP-related signaling. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
PI3K inhibitor, can influence pathways that might intersect with MIIP's role in cell dynamics. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Another PI3K inhibitor, affecting various signaling cascades that could link to MIIP regulations. | ||||||
Dasatinib | 302962-49-8 | sc-358114 sc-358114A | 25 mg 1 g | $70.00 $145.00 | 51 | |
Src kinase inhibitor, can affect cellular adhesion and migration, related to MIIP's function. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $64.00 $246.00 | 136 | |
Inhibits MEK, which could impact the MAPK/ERK pathway and thereby MIIP-associated mechanisms. | ||||||