Date published: 2026-5-30

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IFN-αB Activators

Interferon-alpha B (IFN-αB) activators belong to a class of chemical compounds that play a crucial role in modulating the body's immune response. IFN-αB itself is a type I interferon, which is a group of signaling proteins released by immune cells in response to viral infections and other threats. IFN-αB activators are synthetic or naturally occurring compounds that stimulate the production and activity of IFN-αB in the body. These activators are involved in the regulation of innate and adaptive immune responses and are essential components of the immune system's defense mechanisms.

IFN-αB activators function by binding to specific receptors on the surface of immune cells, particularly dendritic cells and macrophages. This binding initiates a cascade of intracellular signaling events that ultimately lead to the activation of IFN-αB genes and the subsequent synthesis and release of IFN-αB proteins. These proteins then interact with neighboring cells, inducing antiviral and immunomodulatory effects. IFN-αB activators can enhance the body's ability to combat viral infections, regulate inflammatory responses, and promote the development of immune memory. Understanding the mechanisms by which IFN-αB activators work is of great interest in the field of immunology and contributes to our knowledge of the intricate ways the immune system defends the body against pathogens. Researchers continue to investigate the molecular pathways involved in IFN-αB activation and its role in maintaining immune homeostasis.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

R-848

144875-48-9sc-203231
sc-203231A
sc-203231B
sc-203231C
5 mg
25 mg
100 mg
500 mg
$102.00
$306.00
$510.00
$1559.00
12
(1)

An agonist of Toll-like receptors 7 and 8 that can stimulate the production of type I interferons, including IFN-α subtypes.

Imiquimod

99011-02-6sc-200385
sc-200385A
100 mg
500 mg
$67.00
$284.00
6
(1)

A topical immunomodulator that activates immune cells through Toll-like receptor 7, potentially increasing the expression of IFN-α.

Bafilomycin A1

88899-55-2sc-201550
sc-201550A
sc-201550B
sc-201550C
100 µg
1 mg
5 mg
10 mg
$98.00
$255.00
$765.00
$1457.00
280
(6)

An inhibitor of vacuolar-type H+-ATPase that can affect endosomal acidification and may influence Toll-like receptor signaling and IFN-α production.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$123.00
$400.00
148
(1)

A phosphoinositide 3-kinase inhibitor that could modulate cellular signaling pathways, possibly leading to the induction of IFN-α expression.

Emodin

518-82-1sc-202601
sc-202601A
sc-202601B
50 mg
250 mg
15 g
$105.00
$214.00
$6255.00
2
(1)

A natural anthraquinone derivative that has been shown to modulate various cellular signaling pathways with potential effects on IFN-α induction.