Interferon-alpha B (IFN-αB) activators belong to a class of chemical compounds that play a crucial role in modulating the body's immune response. IFN-αB itself is a type I interferon, which is a group of signaling proteins released by immune cells in response to viral infections and other threats. IFN-αB activators are synthetic or naturally occurring compounds that stimulate the production and activity of IFN-αB in the body. These activators are involved in the regulation of innate and adaptive immune responses and are essential components of the immune system's defense mechanisms.
IFN-αB activators function by binding to specific receptors on the surface of immune cells, particularly dendritic cells and macrophages. This binding initiates a cascade of intracellular signaling events that ultimately lead to the activation of IFN-αB genes and the subsequent synthesis and release of IFN-αB proteins. These proteins then interact with neighboring cells, inducing antiviral and immunomodulatory effects. IFN-αB activators can enhance the body's ability to combat viral infections, regulate inflammatory responses, and promote the development of immune memory. Understanding the mechanisms by which IFN-αB activators work is of great interest in the field of immunology and contributes to our knowledge of the intricate ways the immune system defends the body against pathogens. Researchers continue to investigate the molecular pathways involved in IFN-αB activation and its role in maintaining immune homeostasis.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
R-848 | 144875-48-9 | sc-203231 sc-203231A sc-203231B sc-203231C | 5 mg 25 mg 100 mg 500 mg | $102.00 $306.00 $510.00 $1559.00 | 12 | |
An agonist of Toll-like receptors 7 and 8 that can stimulate the production of type I interferons, including IFN-α subtypes. | ||||||
Imiquimod | 99011-02-6 | sc-200385 sc-200385A | 100 mg 500 mg | $67.00 $284.00 | 6 | |
A topical immunomodulator that activates immune cells through Toll-like receptor 7, potentially increasing the expression of IFN-α. | ||||||
Bafilomycin A1 | 88899-55-2 | sc-201550 sc-201550A sc-201550B sc-201550C | 100 µg 1 mg 5 mg 10 mg | $98.00 $255.00 $765.00 $1457.00 | 280 | |
An inhibitor of vacuolar-type H+-ATPase that can affect endosomal acidification and may influence Toll-like receptor signaling and IFN-α production. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
A phosphoinositide 3-kinase inhibitor that could modulate cellular signaling pathways, possibly leading to the induction of IFN-α expression. | ||||||
Emodin | 518-82-1 | sc-202601 sc-202601A sc-202601B | 50 mg 250 mg 15 g | $105.00 $214.00 $6255.00 | 2 | |
A natural anthraquinone derivative that has been shown to modulate various cellular signaling pathways with potential effects on IFN-α induction. | ||||||