IFITM3 Activators
IFITM3 Activators belong to a class of chemical compounds that are associated with the modulation or enhancement of the biological activity of Interferon-Induced Transmembrane Protein 3 (IFITM3), a member of the IFITM family of proteins. IFITM3 is a membrane-associated protein primarily found in the endosomal and lysosomal compartments of cells. These proteins are known for their role in host defense against various pathogens, particularly viruses. IFITM3, in particular, has gained attention for its ability to restrict the entry and replication of a wide range of enveloped viruses, including influenza, SARS-CoV, and other coronaviruses.
IFITM3 Activators are believed to interact with IFITM3, influencing its membrane localization, conformation, or antiviral activity. The precise mechanisms by which these activators modulate IFITM3 function are areas of ongoing research, but it is understood that any alterations in IFITM3 activity can impact the ability of cells to resist viral infection. IFITM3 acts as a potent barrier at the early stages of the viral life cycle by preventing viral fusion and entry into host cells. By targeting IFITM3, these activators enhance or fine-tune the antiviral defenses of host cells against a range of infectious agents. Research in this area is vital for unraveling the molecular mechanisms underlying innate immune responses to viral infections and may provide insights into new strategies for combating viral diseases.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid, a metabolite of vitamin A, influences various cellular processes and has been shown to induce IFITM3 expression, possibly through nuclear receptor signaling. | ||||||
Polyinosinic-polycytidylic acid potassium salt | 31852-29-6 | sc-202767 | 5 mg | $198.00 | ||
Polyinosinic-polycytidylic acid potassium salt mimics viral infection and can stimulate IFITM3 expression as part of the antiviral response. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol, a natural compound found in grapes, has been shown to induce IFITM3 expression, potentially through its antioxidant and anti-inflammatory properties. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin, the active compound in turmeric, can induce IFITM3 expression, possibly through modulation of cellular signaling pathways. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG, a major component of green tea, may induce IFITM3 expression, likely through its antioxidant properties and effects on cellular signaling. | ||||||
Silymarin group, mixture of isomers | 65666-07-1 | sc-301806 | 50 g | $325.00 | ||
Silymarin, extracted from milk thistle, is known to induce IFITM3 expression, potentially through its hepatoprotective and antioxidant effects. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin, a flavonoid found in many plants, can induce IFITM3 expression, possibly through its role in modulating immune responses and cellular signaling. | ||||||