hnRNP CL1 inhibitors constitute a specialized chemical class designed to selectively target and modulate the function of heterogeneous nuclear ribonucleoprotein CL1 (hnRNP CL1). hnRNP CL1 is a member of the heterogeneous nuclear ribonucleoprotein (hnRNP) family, crucial for RNA metabolism and processing. As a specific variant within this family, hnRNP CL1 is characterized by its role in the regulation of pre-mRNA splicing, mRNA transport, and translation. The inhibitors developed for hnRNP CL1 are intricately designed to interact with the specific molecular structure of this ribonucleoprotein, aiming to disrupt its normal interactions within the cellular milieu and potentially influencing RNA-related processes.
The molecular architecture of hnRNP CL1 inhibitors is meticulously crafted to engage specific binding sites on the protein, inducing changes in its conformation and dynamics. This interaction holds the potential to impact the protein's role in RNA processing, including splicing and transport. In laboratory research, these inhibitors serve as invaluable tools, allowing scientists to explore the nuanced functions of hnRNP CL1 in various cellular processes, contributing to a deeper understanding of RNA biology. By manipulating the function of hnRNP CL1, researchers aim to unravel the intricate mechanisms of RNA regulation and the broader implications for cellular function and development. The study of hnRNP CL1 inhibitors stands at the forefront of advancing our comprehension of RNA dynamics and the finely tuned orchestration of cellular processes involved in gene expression.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $74.00 $243.00 $731.00 $2572.00 $21848.00 | 53 | |
Binds to DNA and inhibits RNA polymerase, which can suppress mRNA synthesis. | ||||||
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $269.00 $1050.00 | 26 | |
Inhibitor of RNA polymerase II, potentially decreasing transcription of hnRNPs. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $90.00 $204.00 | 13 | |
Known to inhibit transcription by RNA polymerase II, affecting gene expression. | ||||||
Cordycepin | 73-03-0 | sc-203902 | 10 mg | $101.00 | 5 | |
A nucleoside analog that can terminate RNA transcription and reduce protein levels. | ||||||
DRB | 53-85-0 | sc-200581 sc-200581A sc-200581B sc-200581C | 10 mg 50 mg 100 mg 250 mg | $43.00 $189.00 $316.00 $663.00 | 6 | |
Inhibits RNA polymerase II transcription elongation. | ||||||
Flavopiridol Hydrochloride | 131740-09-5 | sc-207687 | 10 mg | $317.00 | ||
Inhibits cyclin-dependent kinases, which are necessary for RNA polymerase II. | ||||||
Rocaglamide | 84573-16-0 | sc-203241 sc-203241A sc-203241B sc-203241C sc-203241D | 100 µg 1 mg 5 mg 10 mg 25 mg | $275.00 $474.00 $1639.00 $2497.00 $5344.00 | 4 | |
Inhibits translation initiation and has been shown to decrease protein synthesis. | ||||||
Homoharringtonine | 26833-87-4 | sc-202652 sc-202652A sc-202652B | 1 mg 5 mg 10 mg | $52.00 $125.00 $182.00 | 11 | |
Inhibits protein translation initiation, potentially reducing hnRNP protein levels. | ||||||
Anisomycin | 22862-76-6 | sc-3524 sc-3524A | 5 mg 50 mg | $99.00 $259.00 | 36 | |
Inhibits peptide chain elongation, affecting protein synthesis. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $41.00 $84.00 $275.00 | 127 | |
Inhibits eukaryotic protein synthesis by interfering with the translocation step. | ||||||