Date published: 2026-4-1

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hnRNP CL1 Inhibitors

hnRNP CL1 inhibitors constitute a specialized chemical class designed to selectively target and modulate the function of heterogeneous nuclear ribonucleoprotein CL1 (hnRNP CL1). hnRNP CL1 is a member of the heterogeneous nuclear ribonucleoprotein (hnRNP) family, crucial for RNA metabolism and processing. As a specific variant within this family, hnRNP CL1 is characterized by its role in the regulation of pre-mRNA splicing, mRNA transport, and translation. The inhibitors developed for hnRNP CL1 are intricately designed to interact with the specific molecular structure of this ribonucleoprotein, aiming to disrupt its normal interactions within the cellular milieu and potentially influencing RNA-related processes.

The molecular architecture of hnRNP CL1 inhibitors is meticulously crafted to engage specific binding sites on the protein, inducing changes in its conformation and dynamics. This interaction holds the potential to impact the protein's role in RNA processing, including splicing and transport. In laboratory research, these inhibitors serve as invaluable tools, allowing scientists to explore the nuanced functions of hnRNP CL1 in various cellular processes, contributing to a deeper understanding of RNA biology. By manipulating the function of hnRNP CL1, researchers aim to unravel the intricate mechanisms of RNA regulation and the broader implications for cellular function and development. The study of hnRNP CL1 inhibitors stands at the forefront of advancing our comprehension of RNA dynamics and the finely tuned orchestration of cellular processes involved in gene expression.

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
$74.00
$243.00
$731.00
$2572.00
$21848.00
53
(3)

Binds to DNA and inhibits RNA polymerase, which can suppress mRNA synthesis.

α-Amanitin

23109-05-9sc-202440
sc-202440A
1 mg
5 mg
$269.00
$1050.00
26
(2)

Inhibitor of RNA polymerase II, potentially decreasing transcription of hnRNPs.

Triptolide

38748-32-2sc-200122
sc-200122A
1 mg
5 mg
$90.00
$204.00
13
(1)

Known to inhibit transcription by RNA polymerase II, affecting gene expression.

Cordycepin

73-03-0sc-203902
10 mg
$101.00
5
(1)

A nucleoside analog that can terminate RNA transcription and reduce protein levels.

DRB

53-85-0sc-200581
sc-200581A
sc-200581B
sc-200581C
10 mg
50 mg
100 mg
250 mg
$43.00
$189.00
$316.00
$663.00
6
(1)

Inhibits RNA polymerase II transcription elongation.

Flavopiridol Hydrochloride

131740-09-5sc-207687
10 mg
$317.00
(2)

Inhibits cyclin-dependent kinases, which are necessary for RNA polymerase II.

Rocaglamide

84573-16-0sc-203241
sc-203241A
sc-203241B
sc-203241C
sc-203241D
100 µg
1 mg
5 mg
10 mg
25 mg
$275.00
$474.00
$1639.00
$2497.00
$5344.00
4
(1)

Inhibits translation initiation and has been shown to decrease protein synthesis.

Homoharringtonine

26833-87-4sc-202652
sc-202652A
sc-202652B
1 mg
5 mg
10 mg
$52.00
$125.00
$182.00
11
(1)

Inhibits protein translation initiation, potentially reducing hnRNP protein levels.

Anisomycin

22862-76-6sc-3524
sc-3524A
5 mg
50 mg
$99.00
$259.00
36
(2)

Inhibits peptide chain elongation, affecting protein synthesis.

Cycloheximide

66-81-9sc-3508B
sc-3508
sc-3508A
100 mg
1 g
5 g
$41.00
$84.00
$275.00
127
(6)

Inhibits eukaryotic protein synthesis by interfering with the translocation step.