Date published: 2025-11-24

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HHV-8 Activators

HHV-8 activators constitute a specialized chemical class of compounds recognized for their capacity to influence the activation of HHV-8, or Human Herpesvirus 8, also known as Kaposi's Sarcoma-Associated Herpesvirus (KSHV). These activators are designed to interact with the HHV-8 virus or its associated cellular machinery, potentially promoting viral replication and gene expression. At the molecular level, the mechanisms through which HHV-8 activators exert their effects can be multifaceted, and they may involve interactions with specific viral proteins or cellular factors that are critical for the virus's life cycle.

The study of HHV-8 activators is instrumental in advancing our understanding of the molecular intricacies and their interaction with host cells. Researchers in this field primarily focus on elucidating the precise molecular mechanisms by which these compounds impact HHV-8's activation and replication. Understanding the role of HHV-8 activators contributes to our broader knowledge of viral pathogenesis and the complex interplay between viruses and their host cells. Moreover, these compounds serve as valuable tools for scientists seeking to investigate the underlying molecular events that drive HHV-8 infections, ultimately deepening our comprehension of herpesvirus biology and its potential implications in various scientific and biomedical contexts.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

PMA

16561-29-8sc-3576
sc-3576A
sc-3576B
sc-3576C
sc-3576D
1 mg
5 mg
10 mg
25 mg
100 mg
$40.00
$129.00
$210.00
$490.00
$929.00
119
(6)

A known stimulator of protein kinase C (PKC); induces lytic reactivation of HHV-8.

Sodium Butyrate

156-54-7sc-202341
sc-202341B
sc-202341A
sc-202341C
250 mg
5 g
25 g
500 g
$30.00
$46.00
$82.00
$218.00
19
(3)

Histone deacetylase inhibitor; promotes viral gene expression and lytic reactivation.

Valproic Acid

99-66-1sc-213144
10 g
$85.00
9
(1)

Another histone deacetylase inhibitor; can induce HHV-8 reactivation in cells.

Dexamethasone

50-02-2sc-29059
sc-29059B
sc-29059A
100 mg
1 g
5 g
$76.00
$82.00
$367.00
36
(1)

A glucocorticoid that can modulate various gene expressions; potential influence on HHV-8 reactivation.

β-Estradiol

50-28-2sc-204431
sc-204431A
500 mg
5 g
$62.00
$178.00
8
(1)

Affects various signaling pathways; could potentially modulate HHV-8 expression or reactivation.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$62.00
$155.00
$320.00
233
(4)

mTOR inhibitor; might have an effect on HHV-8 replication and reactivation.

Cyclosporin A

59865-13-3sc-3503
sc-3503-CW
sc-3503A
sc-3503B
sc-3503C
sc-3503D
100 mg
100 mg
500 mg
10 g
25 g
100 g
$62.00
$90.00
$299.00
$475.00
$1015.00
$2099.00
69
(5)

Immunosuppressant that may influence HHV-8 reactivation,

Hydrocortisone

50-23-7sc-300810
5 g
$100.00
6
(1)

Another glucocorticoid; potential to influence HHV-8 latency and reactivation.

Progesterone

57-83-0sc-296138A
sc-296138
sc-296138B
1 g
5 g
50 g
$20.00
$51.00
$292.00
3
(1)

Might influence HHV-8 replication or reactivation through hormonal pathways.