hedgehog Activators
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
CUR 61414 | 334998-36-6 | sc-211143 | 1 mg | $380.00 | 1 | |
CUR 61414 functions as a selective hedgehog pathway modulator, characterized by its ability to disrupt the interaction between key signaling proteins. Its unique structural features enable it to bind specifically to the receptor, altering downstream signaling cascades. This modulation affects cellular responses by influencing gene expression patterns and cellular differentiation. The compound's distinct interaction kinetics and affinity contribute to its nuanced role in regulating developmental processes. | ||||||
SAG | 912545-86-9 | sc-212905 sc-212905A | 1 mg 5 mg | $163.00 $413.00 | 27 | |
Directly activates the Smoothened (SMO) receptor, a critical component of the Hedgehog signaling pathway, by binding to its transmembrane domain. | ||||||
Purmorphamine | 483367-10-8 | sc-202785 sc-202785A | 1 mg 5 mg | $56.00 $180.00 | 18 | |
Activates the Hedgehog signaling pathway by targeting the Smoothened (SMO) receptor, thus mimicking the effect of the Hedgehog ligand. | ||||||
GANT61 | 500579-04-4 | sc-202630 sc-202630A sc-202630B | 1 mg 5 mg 10 mg | $63.00 $128.00 $200.00 | 6 | |
Disrupts GLI-mediated transcription, an essential downstream component of the Hedgehog signaling pathway, indirectly enhancing pathway activation. | ||||||
Cyclopamine | 4449-51-8 | sc-200929 sc-200929A | 1 mg 5 mg | $92.00 $204.00 | 19 | |
Can cause non-canonical activation of the Hedgehog pathway by binding to Smoothened (SMO). | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Activates adenylyl cyclase, leading to cAMP accumulation, which can indirectly influence the Hedgehog signaling pathway. | ||||||
Jervine | 469-59-0 | sc-200934 sc-200934A | 1 mg 5 mg | $66.00 $240.00 | 1 | |
Interacts with Smoothened (SMO), leading to non-canonical activation of the Hedgehog signaling pathway. | ||||||
Cholesterol | 57-88-5 | sc-202539C sc-202539E sc-202539A sc-202539B sc-202539D sc-202539 | 5 g 5 kg 100 g 250 g 1 kg 25 g | $26.00 $2754.00 $126.00 $206.00 $572.00 $86.00 | 11 | |
A precursor to oxysterols, which can activate the Smoothened receptor, thus playing a role in activating the Hedgehog pathway. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $70.00 $160.00 $290.00 | 2 | |
Influences the Hedgehog signaling pathway, particularly in the context of cell differentiation and proliferation. | ||||||
Tomatidine hydrochloride | 6192-62-7 | sc-200931 | 25 mg | $66.00 | 1 | |
Modulates the Hedgehog pathway, though the exact mechanism remains less clear. | ||||||