HDAC1 Inhibitors
Santa Cruz Biotechnology now offers a broad range of HDAC1 Inhibitors. Histone deacetylase proteins (HDACs) are a class of enzymes that remove acetyl groups (O=C-CH3) from an <ε>-N-acetyl lysine amino acid on a histone, allowing histones to wrap DNA more tightly. The deacetylation of histones is associated with transcriptional silencing. Histone deacetylase inhibitors (HDIs) have a long history of use in psychiatry and neurology as mood stabilizers and anti-epileptic. HDIs are studied as a treatment for neurodegenerative diseases and have a potential for cancer therapy. HDAC1 Inhibitors offered by Santa Cruz inhibit HDAC1 and, in some cases, other chromatin remodeling and transcription regulation related proteins. View detailed HDAC1 Inhibitor specifications, including HDAC1 Inhibitor CAS number, molecular weight, molecular formula and chemical structure, by clicking on the product name.
Items 11 to 20 of 27 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Romidepsin | 128517-07-7 | sc-364603 sc-364603A | 1 mg 5 mg | $218.00 $634.00 | 1 | |
Romidepsin binds to the active site of HDAC1, blocking its deacetylase function and causing epigenetic changes in gene expression. | ||||||
CI 994 | 112522-64-2 | sc-205245 sc-205245A | 10 mg 50 mg | $99.00 $536.00 | 1 | |
CI-994 targets HDAC1, leading to histone hyperacetylation and affecting gene transcription and epigenetic regulation. | ||||||
Panobinostat | 404950-80-7 | sc-208148 | 10 mg | $200.00 | 9 | |
Panobinostat inhibits HDAC1 by binding to its active site, leading to hyperacetylation of histones and influencing gene expression. | ||||||
Mocetinostat | 726169-73-9 | sc-364539 sc-364539B sc-364539A | 5 mg 10 mg 50 mg | $214.00 $247.00 $1463.00 | 2 | |
Mocetinostat inhibits HDAC1, causing an increase in histone acetylation and influencing the expression of genes involved in epigenetic processes. | ||||||
Pimelic Diphenylamide 106 | 937039-45-7 | sc-364589 sc-364589A | 1 mg 5 mg | $41.00 $74.00 | ||
Pimelic Diphenylamide 106 (CAS 937039-45-7) functions as an HDAC1 inhibitor, impacting cellular gene regulation. Its interaction with HDAC1 leads to modifications in epigenetic mechanisms, affecting cellular processes without broader implications. | ||||||
TC-H 106 | 937039-45-7 | sc-362801 sc-362801A | 10 mg 50 mg | $155.00 $620.00 | ||
TC-H 106 (CAS 937039-45-7) acts as an HDAC1 inhibitor, influencing cellular gene regulation. By interacting with HDAC1, it brings about changes in epigenetic mechanisms, impacting cellular processes exclusively. | ||||||
Tubastatin A | 1252003-15-8 | sc-507298 | 10 mg | $114.00 | ||
Tubastatin A is a selective HDAC6 inhibitor, affecting HDAC1 indirectly by modulating tubulin acetylation and influencing chromatin remodeling. | ||||||
KD 5170 | 940943-37-3 | sc-362755 | 10 mg | $398.00 | ||
KD 5170 (CAS 940943-37-3) functions as an HDAC1 inhibitor, modulating cellular gene regulation processes. Its interaction with HDAC1 brings about changes in epigenetic mechanisms, affecting cellular functions without broader implications. | ||||||
MC 1293 | sc-221875 | 5 mg | $202.00 | 1 | ||
MC 1293 functions as a selective HDAC1 inhibitor, characterized by its ability to form stable interactions with the enzyme's catalytic domain. Its unique structural features enable it to engage in hydrogen bonding and hydrophobic interactions, enhancing binding affinity. This compound modulates the deacetylation process, influencing the dynamics of histone modifications and chromatin remodeling, thereby impacting transcriptional regulation and cellular signaling pathways. | ||||||
CBHA | 174664-65-4 | sc-205240 sc-205240A | 5 mg 25 mg | $132.00 $395.00 | 2 | |
CBHA (CAS 174664-65-4) acts as an HDAC1 inhibitor, impacting cellular gene regulation processes. Through its interaction with HDAC1, it induces changes in epigenetic mechanisms, influencing cellular functions without broader implications. | ||||||