GPR35 Inhibitors
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Items 1 to 10 of 13 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
ML 145 | 1164500-72-4 | sc-361254 sc-361254A | 10 mg 50 mg | $225.00 $930.00 | ||
ML 145 acts as a selective GPR35 modulator, exhibiting unique binding characteristics that enhance receptor affinity. Its structure allows for specific hydrophobic interactions with the receptor's binding pocket, promoting conformational changes that activate downstream signaling pathways. The compound's ability to stabilize receptor dimers may influence GPR35's role in various cellular processes. Additionally, its kinetic profile suggests a rapid onset of action, making it a compelling candidate for further exploration in receptor biology. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
A broad-spectrum kinase inhibitor, may affect downstream signaling pathways of GPR35. | ||||||
CID 2745687 | 264233-05-8 | sc-362725 sc-362725A | 10 mg 50 mg | $200.00 $800.00 | 1 | |
CID 2745687 serves as a selective modulator of GPR35, characterized by its unique ability to engage in specific electrostatic interactions with the receptor. This compound promotes distinct conformational shifts that facilitate the activation of intracellular signaling cascades. Its structural features enable it to influence receptor oligomerization, potentially altering GPR35's functional dynamics. The compound's interaction kinetics indicate a nuanced engagement with the receptor, suggesting a complex regulatory role in cellular signaling networks. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
PI3K inhibitor, can modulate pathways downstream of GPR35 activation. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
Inhibits MEK, a part of the MAPK/ERK pathway, potentially influencing GPR35-related signaling. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
Another MEK inhibitor, could impact MAPK/ERK pathway associated with GPR35 signaling. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Inhibits PI3K, could affect PI3K/Akt pathway activated by GPR35. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
mTOR inhibitor, can influence downstream effects of GPR35 activation. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
p38 MAPK inhibitor, may modulate stress response pathways related to GPR35. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
Inhibits JNK, potentially affecting signaling pathways involving GPR35. | ||||||