ML 145 (CAS 1164500-72-4)

건강 상태 :

Solid

용해도 :

Soluble in DMSO (100 mM).

저장 :

Store at -20° C

녹는점 :

349.84° C (Predicted)

비등점 :

797.97° C (Predicted)

밀도 :

~1.5 g/cm³ (Predicted)

굴절률 :

n²⁰_D 1.72 (Predicted)

IC50 :

GPR35: IC₅₀ = 27 nM (human); HePTP: IC₅₀ = 0.70 µM (human); Mcl-1: IC₅₀ = 1.56 µM (human); PTP-PEST: IC₅₀ = 9.91 µM (human); PTP22: IC₅₀ = 37.9 µM (human)

Ki 데이타 :

GPR35: K_i= 8.76 nM (human)

pK 값 :

pK_a: 3.08 (Predicted)

수송 :

Not available for sale outside of the United States.

PubChem CID :

MDL 번호 :

MFCD03705956

SMILES :

C/C(=C\\C1=CC=CC=C1)/C=C\\2/C(=O)N(C(=S)S2)CCCC(=O)NC3=CC(=C(C=C3)C(=O)O)O