Date published: 2025-12-24

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GPR172A Inhibitors

GPR172A inhibitors belong to a category of chemical compounds designed to specifically target and modulate the activity of the GPR172A protein. GPR172A, also known as G protein-coupled receptor 172A, is a type of cell surface receptor protein belonging to the G protein-coupled receptor (GPCR) family. GPCRs are integral membrane proteins that play essential roles in cellular signal transduction and communication. GPR172A, in particular, is known to be expressed in various tissues and is believed to be involved in mediating cellular responses to certain extracellular signals or ligands. Inhibitors designed to target GPR172A are developed to interfere with its normal signaling function, and they may do so through various mechanisms. The precise mechanisms of action of GPR172A inhibitors can vary based on their chemical structures and binding properties. Some inhibitors may bind directly to GPR172A, preventing its interaction with specific ligands or downstream signaling partners. Others may modulate the receptor's conformation or activity, influencing its downstream signaling pathways. By inhibiting GPR172A, these compounds have the potential to impact cellular processes that are regulated by this receptor, such as intracellular signaling cascades, gene expression, or cellular responses to external stimuli. Ongoing research is focused on elucidating the detailed mechanisms and physiological functions of GPR172A, as well as the development and characterization of inhibitors that can help researchers better understand its role in cellular biology.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Nicotinamide

98-92-0sc-208096
sc-208096A
sc-208096B
sc-208096C
100 g
250 g
1 kg
5 kg
$43.00
$65.00
$200.00
$815.00
6
(1)

Nicotinamide, a form of vitamin B3, may theoretically influence GPR172A expression due to its role in NAD+ biosynthesis, which is interconnected with riboflavin metabolism.

Chloroquine

54-05-7sc-507304
250 mg
$68.00
2
(0)

Chloroquine, known for its antimalarial properties, might affect GPR172A expression indirectly through its impact on lysosomal function and cellular autophagy processes.

Methotrexate

59-05-2sc-3507
sc-3507A
100 mg
500 mg
$92.00
$209.00
33
(5)

Methotrexate, an antimetabolite, might influence GPR172A expression through its effects on folate metabolism, which is connected to overall cellular metabolism.

Rifampicin

13292-46-1sc-200910
sc-200910A
sc-200910B
sc-200910C
1 g
5 g
100 g
250 g
$95.00
$322.00
$663.00
$1438.00
6
(1)

Rifampicin could affect GPR172A expression by altering liver enzyme activity, potentially impacting riboflavin metabolism.

Isoniazid

54-85-3sc-205722
sc-205722A
sc-205722B
5 g
50 g
100 g
$25.00
$99.00
$143.00
(1)

Isoniazid might affect GPR172A expression indirectly via its influence on liver metabolism and nutrient absorption.

Omeprazole

73590-58-6sc-202265
50 mg
$66.00
4
(1)

Omeprazole, a proton pump inhibitor, could potentially impact GPR172A expression through alterations in gastric pH, affecting nutrient absorption including riboflavin.

Lead

7439-92-1sc-250236
2 kg
$102.00
(0)

Exposure to lead can disrupt various biological processes, potentially including those related to riboflavin transport and GPR172A expression.

Arsenic sponge

7440-38-2sc-278710
25 g
$236.00
(0)

Arsenic, a toxic element, could affect GPR172A expression through its broad impact on cellular metabolism and oxidative stress.