Date published: 2026-5-5

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gp130 Antibodies

Santa Cruz Biotechnology features a diverse variety of gp130 monoclonal antibodies for research focused on understanding the complex signaling pathways mediated by gp130. gp130 Antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). gp130 is a critical component of the interleukin-6 (IL-6) receptor complex, playing a vital role in mediating inflammatory responses and hematopoiesis. gp130 is involved in various cellular processes, including cell survival, proliferation, and differentiation, making it an important target for research in immunology and cancer biology. Understanding gp130 function is essential for elucidating its role in disease mechanisms and potential therapeutic interventions. Researchers worldwide rely on gp130 monoclonal antibodies to advance their studies in signal transduction pathways. gp130 monoclonal antibodies enable detailed investigation of protein expression patterns and interactions in various biological systems. Santa Cruz Biotechnology monoclonal antibodies for gp130 continue to support breakthrough discoveries in cellular and molecular biology research.

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gp130 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

CD130/gp130 Antibody (E-8)

sc-376280mouse IgG2a κ365-619 (h)WB, IP, IF, IHC(P), ELISAm, r, h
31
(12)

CD130/gp130 Antibody (AN-H2)

sc-9994mouse IgG1 κ(h)WB, IP, IF, IHC(P), FCM, ELISAh
10
(5)

Phospho-Specific gp130 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

p-CD130/gp130 Antibody (A-12)

sc-377572mouse IgG2a κSer 782 (h)WB, IP, IF, IHC(P), ELISAm, r, h
4
(4)

p-CD130/gp130 Antibody (D-3)

sc-377570mouse IgG2b κSer 782 (h)WB, IP, IF, ELISAm, r, h

new

(2)

gp130 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

CD130/gp130 CRISPR/Cas9 KO Plasmid (h)

sc-400301hGene KnockoutGFP0
(0)

CD130/gp130 HDR Plasmid (h)

sc-400301-HDRhHomology Directed RepairPuromycin0
(0)

CD130/gp130 Double Nickase Plasmid (h)

sc-400301-NIChGene KnockoutPuromycin0
(0)

CD130/gp130 Double Nickase Plasmid (h2)

sc-400301-NIC-2hGene KnockoutPuromycin0
(0)

CD130/gp130 CRISPR/Cas9 KO Plasmid (m)

sc-421116mGene KnockoutGFP0
(0)

CD130/gp130 HDR Plasmid (m)

sc-421116-HDRmHomology Directed RepairPuromycin0
(0)

gp130 CRISPR Activation Products

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CD130/gp130 CRISPR Activation Plasmid (h)

sc-400301-ACThGene ActivationPuro, Blast, Hygro0
(0)

CD130/gp130 CRISPR Activation Plasmid (h2)

sc-400301-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

gp130 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

CD130/gp130 siRNA (h)

sc-29333hGene SilencingN/A
5
(0)

CD130/gp130 shRNA Plasmid (h)

sc-29333-SHhGene SilencingPuromycin
5
(0)

CD130/gp130 shRNA (h) Lentiviral Particles

sc-29333-VhGene SilencingPuromycin
5
(0)

CD130/gp130 siRNA (m)

sc-35502mGene SilencingN/A
5
(0)

CD130/gp130 shRNA Plasmid (m)

sc-35502-SHmGene SilencingPuromycin
5
(0)

CD130/gp130 shRNA (m) Lentiviral Particles

sc-35502-VmGene SilencingPuromycin
5
(0)