The protein GOLT1B, also known as Golgi transport 1B, is a member of the golgin family and is involved in maintaining the structure and function of the Golgi apparatus. This protein is essential for the process of vesicular transport, a key mechanism in cell function.The Golgi apparatus is an organelle in eukaryotic cells that sorts and modifies proteins and lipids for transport to their final destinations. It's a critical part of the cell's endomembrane system. GOLT1B is one of the many proteins involved in regulating the movement of vesicles to, from, and within the Golgi.
GOLT1B is a transmembrane protein, meaning it spans the membrane of the Golgi apparatus. It's believed to function as a tether, helping to guide vesicles to their correct destinations within the Golgi. It may also help in maintaining the structure of the Golgi, which is composed of a series of flattened stacks of membranes.bnormalities in Golgi function and vesicle transport have been linked to various diseases, including neurological disorders and cancer, highlighting the importance of proteins like GOLT1B.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $31.00 $53.00 $124.00 $374.00 | 25 | |
Brefeldin A disrupts Golgi structure and function, which could indirectly influence GOLT1B activity in Golgi reassembly and transport processes. | ||||||
Monensin A | 17090-79-8 | sc-362032 sc-362032A | 5 mg 25 mg | $155.00 $525.00 | ||
Monensin affects Golgi apparatus function and might indirectly impact GOLT1B-related protein transport pathways. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin increases cAMP levels, potentially influencing various intracellular transport processes including those related to GOLT1B. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $59.00 $85.00 $143.00 $247.00 | 38 | |
Nocodazole disrupts microtubules, affecting intracellular transport and potentially influencing GOLT1B function indirectly. | ||||||
Golgicide A | 1005036-73-6 | sc-215103 sc-215103A | 5 mg 25 mg | $191.00 $683.00 | 11 | |
Golgicide A specifically targets the Golgi apparatus, potentially impacting GOLT1B-related pathways in Golgi function and maintenance. | ||||||
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $172.00 $305.00 | 66 | |
Tunicamycin inhibits N-linked glycosylation, affecting protein folding and transport in the Golgi, potentially impacting GOLT1B function. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $136.00 $446.00 | 114 | |
Thapsigargin disrupts calcium homeostasis, affecting Golgi function and possibly GOLT1B-related processes. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $69.00 | 2 | |
Chloroquine affects endosomal and lysosomal function, which might indirectly impact GOLT1B-related Golgi functions. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin inhibits mTOR, influencing cellular growth and protein transport, potentially affecting GOLT1B. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium impacts several signaling pathways, including those related to intracellular transport, possibly intersecting with GOLT1B functions. | ||||||