The chemical class known as GOLGA8H Activators encompasses a varied group of compounds that have the capacity to influence the functionality of the protein GOLGA8H. This protein, a member of the golgin subfamily of coiled-coil proteins, plays a pivotal role in the structural organization and functioning of the Golgi apparatus, an essential organelle in the cell. The activators in this class are not characterized by a uniform chemical structure or a common mechanism of action. Instead, they are linked by their potential interaction with the cellular pathways and processes in which GOLGA8H is involved. These compounds may act by modulating the dynamics of the Golgi apparatus, either by direct interaction with its components or through indirect influence on related cellular pathways. The diversity of these chemicals reflects the complexity of the cellular processes and the intricate network of interactions within which GOLGA8H functions.
In this class, compounds range from those affecting intracellular signaling molecules to agents that impact the structural integrity of cellular components. For example, some activators might work by altering the levels of secondary messengers like cAMP, thereby affecting the signaling pathways related to the Golgi apparatus and GOLGA8H. Others could directly target the Golgi apparatus, influencing its structure and function, and thereby modulating the activity of GOLGA8H. Such diversity in the mechanisms of action of these compounds underscores the multifaceted nature of GOLGA8H's role within the cell. The array of chemicals classified as GOLGA8H Activators thus serves not only as a means to explore the functional aspects of GOLGA8H but also as a tool to understand the broader context of Golgi apparatus dynamics in cellular biology. Through their interactions with various cellular processes, these compounds can shed light on the intricate balance and coordination required for the proper functioning of the Golgi apparatus, and by extension, the role played by GOLGA8H in maintaining this balance.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
Activates protein kinase C, possibly impacting Golgi function and GOLGA8H interaction. | ||||||
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $31.00 $53.00 $124.00 $374.00 | 25 | |
Known to disrupt Golgi structure; could hypothetically alter GOLGA8H's functional state. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $59.00 $85.00 $143.00 $247.00 | 38 | |
A microtubule disruptor that might affect Golgi apparatus dynamics and hence GOLGA8H activity. | ||||||
Monensin A | 17090-79-8 | sc-362032 sc-362032A | 5 mg 25 mg | $155.00 $525.00 | ||
Affects Golgi apparatus ion balance; might indirectly influence GOLGA8H. | ||||||
Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $165.00 $486.00 | 64 | |
Disrupts actin filaments, potentially affecting Golgi organization and GOLGA8H function. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $69.00 | 2 | |
Known to affect endosomal-lysosomal system; could indirectly impact GOLGA8H. | ||||||
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $172.00 $305.00 | 66 | |
Affects N-linked glycosylation in the ER, potentially influencing Golgi and GOLGA8H. | ||||||
Golgicide A | 1005036-73-6 | sc-215103 sc-215103A | 5 mg 25 mg | $191.00 $683.00 | 11 | |
Specifically targets the Golgi, might interact with or influence GOLGA8H indirectly. | ||||||