Date published: 2025-12-8

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GMF-β Activators

The chemical class of compounds referred to as GMF-β Activators encompasses a range of chemicals designed to influence cellular processes associated with Glial Maturation Factor beta (GMF-β), a protein implicated in the regulation of the actin cytoskeleton dynamics. The identified compounds focus on modulating actin-related pathways rather than direct activation of GMF-β due to limited specific information on direct activators. These compounds are selected based on their known effects on cellular processes involving actin polymerization, a key element of the cytoskeleton. Activators of this class disrupt actin polymerization, consequently affecting cellular dynamics associated with GMF-β.

GMF-β Activators influence actin stability and filament formation, potentially impacting GMF-β-mediated regulatory mechanisms. Additionally, inhibitors targeting specific pathways related to actin dynamics may indirectly influence GMF-β by modulating upstream factors. This diverse array of compounds showcases the multifaceted strategies that could be employed to manipulate cellular processes linked to GMF-β, underscoring the complexity of actin cytoskeleton regulation. While the direct activation of GMF-β may not be fully elucidated, these compounds serve as putative tools to study and understand the intricate network of cellular processes associated with GMF-β function. The chemical class of GMF-β activators is conceptualized to provide researchers with a set of tools for investigating the intricate regulatory mechanisms of GMF-β and its involvement in actin dynamics, contributing to the broader understanding of cellular processes influenced by this protein.

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Latrunculin A, Latrunculia magnifica

76343-93-6sc-202691
sc-202691B
100 µg
500 µg
$260.00
$799.00
36
(2)

Disrupts actin polymerization, potentially impacting cellular processes involving GMF-β.

Cytochalasin D

22144-77-0sc-201442
sc-201442A
1 mg
5 mg
$145.00
$442.00
64
(4)

Inhibits actin polymerization, indirectly influencing cellular dynamics associated with GMF-β.

Jasplakinolide

102396-24-7sc-202191
sc-202191A
50 µg
100 µg
$180.00
$299.00
59
(1)

Stabilizes actin filaments, potentially affecting GMF-β-mediated actin cytoskeleton regulation.

Y-27632, free base

146986-50-7sc-3536
sc-3536A
5 mg
50 mg
$182.00
$693.00
88
(1)

Rho-associated protein kinase (ROCK) inhibitor, indirectly impacting actin dynamics and GMF-β regulation.

CK 666

442633-00-3sc-361151
sc-361151A
10 mg
50 mg
$315.00
$1020.00
5
(0)

Arp2/3 complex inhibitor, affecting actin polymerization dynamics, which may have downstream effects on GMF-β.

PFI-1

1403764-72-6sc-478504
5 mg
$96.00
(0)

Formin inhibitor, potentially impacting actin filament formation and cellular processes related to GMF-β.

(±)-Blebbistatin

674289-55-5sc-203532B
sc-203532
sc-203532A
sc-203532C
sc-203532D
5 mg
10 mg
25 mg
50 mg
100 mg
$179.00
$307.00
$455.00
$924.00
$1689.00
7
(1)

Myosin II inhibitor, influencing actin-myosin interactions and, by extension, processes associated with GMF-β.

Wiskostatin

253449-04-6sc-204399
sc-204399A
sc-204399B
sc-204399C
1 mg
5 mg
25 mg
50 mg
$48.00
$122.00
$432.00
$812.00
4
(1)

Cdc42 and Rac1 inhibitor, potentially impacting actin dynamics regulated by GMF-β.

Cdc7/Cdk9 Inhibitor

845714-00-3sc-311303
5 mg
$270.00
1
(1)

Disrupts Arp2/3 complex function, influencing actin polymerization dynamics, and cellular processes associated with GMF-β.

Latrunculin B

76343-94-7sc-203318
1 mg
$229.00
29
(1)

Similar to Latrunculin A, disrupts actin polymerization, potentially influencing GMF-β-mediated cellular processes.