GIT2 Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Sorafenib | 284461-73-0 | sc-220125 sc-220125A sc-220125B | 5 mg 50 mg 500 mg | $57.00 $100.00 $250.00 | 129 | |
Sorafenib is a multi-kinase inhibitor that targets various receptors, including VEGFR, PDGFR, and RAF kinases. Inhibition of these kinases can alter GIT2-related signaling pathways, particularly those involved in cell proliferation and survival. | ||||||
Dasatinib | 302962-49-8 | sc-358114 sc-358114A | 25 mg 1 g | $70.00 $145.00 | 51 | |
Dasatinib is a tyrosine kinase inhibitor that primarily targets BCR-ABL and Src family kinases. It can affect GIT2-related pathways by modulating downstream signaling of integrins and other membrane receptors that engage GIT2. | ||||||
Nilotinib | 641571-10-0 | sc-202245 sc-202245A | 10 mg 25 mg | $209.00 $413.00 | 9 | |
Nilotinib is a selective inhibitor of BCR-ABL kinase, which can indirectly affect GIT2 signaling by altering the balance of downstream pathways that may intersect with GIT2 regulatory networks. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002 is a PI3K inhibitor that impacts the AKT/PKB signaling pathway. Since GIT2 can interact with components of the PI3K pathway, inhibition of PI3K can modulate GIT2-associated cellular functions. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
PD98059 is a MEK inhibitor that prevents the activation of MAPK/ERK. It can influence GIT2 activity by altering the MAPK signaling cascade, which is potentially linked to GIT2 functions. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 is an inhibitor of JNK, which may impact GIT2 signaling by modulating stress- and inflammation-related pathways where GIT2 might play a role. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Wortmannin is a potent and irreversible inhibitor of PI3K, which can affect GIT2 signaling through its role in membrane trafficking and signal transduction pathways associated with GIT2. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin is an mTOR inhibitor that can indirectly influence GIT2 by modulating the mTOR signaling pathways involved in cell growth, proliferation, and survival. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
Y-27632 is a ROCK inhibitor that can affect GIT2 signaling by altering the actin cytoskeleton dynamics and cell motility processes where GIT2 is implicated. | ||||||
PP 2 | 172889-27-9 | sc-202769 sc-202769A | 1 mg 5 mg | $94.00 $227.00 | 30 | |
PP2 is an Src family kinase inhibitor that can modulate GIT2 signaling pathways by affecting integrin signaling and cytoskeletal organization. | ||||||