GGT6, an enzyme crucial in glutathione metabolism, plays a significant role in cellular detoxification and antioxidant defense. The functional activity of GGT6 can be influenced by various chemical compounds that modulate glutathione levels and related metabolic pathways. Compounds like Glutathione, N-Acetylcysteine, and Cysteine, which are directly involved in glutathione metabolism, can enhance GGT6 activity by increasing the availability of its substrate or by boosting intracellular glutathione levels. The presence of these compounds can lead to an increased demand for GGT6's activity in processing glutathione for antioxidant defense and amino acid transport.
Other compounds such as Sulfasalazine, and Oltipraz, which interact with glutathione or influence its metabolism, can also enhance GGT6 activity. Sulfasalazine, by affecting glutathione levels, and Oltipraz, by inducing phase II detoxification enzymes, can create conditions that necessitate increased GGT6 activity. Additionally, compounds like Alpha-Lipoic Acid, Curcumin, Selenium, and Vitamin C, which influence the cellular redox status and antioxidant pathways, can indirectly augment the role of GGT6 in maintaining oxidative balance and detoxification.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Glutathione, reduced | 70-18-8 | sc-29094 sc-29094A | 10 g 1 kg | $82.00 $2091.00 | 8 | |
As the substrate for GGT enzymes, increased levels of GSH could enhance GGT6 activity in glutathione metabolism. | ||||||
N-Acetyl-L-cysteine | 616-91-1 | sc-202232 sc-202232A sc-202232C sc-202232B | 5 g 25 g 1 kg 100 g | $34.00 $74.00 $270.00 $114.00 | 34 | |
A precursor to glutathione, NAC can increase intracellular glutathione levels, potentially enhancing GGT6 activity. | ||||||
Sulfasalazine | 599-79-1 | sc-204312 sc-204312A sc-204312B sc-204312C | 1 g 2.5 g 5 g 10 g | $61.00 $77.00 $128.00 $209.00 | 8 | |
As a drug that affects glutathione levels, Sulfasalazine might indirectly enhance GGT6 activity in cellular detoxification. | ||||||
L-Cysteine | 52-90-4 | sc-286072 sc-286072A sc-286072B sc-286072C sc-286072D | 25 g 100 g 500 g 5 kg 10 kg | $51.00 $112.00 $449.00 $1151.00 $2178.00 | 1 | |
As a key amino acid in glutathione synthesis, increased cysteine levels can indirectly enhance GGT6 activity by boosting glutathione availability. | ||||||
L-Methionine | 63-68-3 | sc-394076 sc-394076A sc-394076B sc-394076C sc-394076D sc-394076E | 25 g 100 g 250 g 1 kg 5 kg 10 kg | $34.00 $37.00 $57.00 $151.00 $577.00 $1103.00 | ||
Methionine, involved in glutathione synthesis, can indirectly influence GGT6 activity through its role in glutathione metabolism. | ||||||
α-Lipoic Acid | 1077-28-7 | sc-202032 sc-202032A sc-202032B sc-202032C sc-202032D | 5 g 10 g 250 g 500 g 1 kg | $69.00 $122.00 $212.00 $380.00 $716.00 | 3 | |
As an antioxidant, Alpha-Lipoic Acid can influence cellular redox status, potentially enhancing GGT6 activity in maintaining oxidative balance. | ||||||
Oltipraz | 64224-21-1 | sc-205777 sc-205777A | 500 mg 1 g | $286.00 $622.00 | ||
Oltipraz induces phase II detoxification enzymes, including GGT, potentially enhancing GGT6 activity in detoxification pathways. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin can modulate glutathione levels and oxidative stress response, potentially influencing GGT6 activity. | ||||||
Selenium | 7782-49-2 | sc-250973 | 50 g | $62.00 | 1 | |
Selenium is important for glutathione metabolism. Adequate selenium levels can indirectly enhance GGT6 activity. | ||||||
L-Ascorbic acid, free acid | 50-81-7 | sc-202686 | 100 g | $46.00 | 5 | |
Vitamin C can regenerate glutathione from its oxidized form, potentially increasing the functional demand for GGT6 in glutathione metabolism. | ||||||