Date published: 2026-2-22

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GGT6 Activators

GGT6, an enzyme crucial in glutathione metabolism, plays a significant role in cellular detoxification and antioxidant defense. The functional activity of GGT6 can be influenced by various chemical compounds that modulate glutathione levels and related metabolic pathways. Compounds like Glutathione, N-Acetylcysteine, and Cysteine, which are directly involved in glutathione metabolism, can enhance GGT6 activity by increasing the availability of its substrate or by boosting intracellular glutathione levels. The presence of these compounds can lead to an increased demand for GGT6's activity in processing glutathione for antioxidant defense and amino acid transport.

Other compounds such as Sulfasalazine, and Oltipraz, which interact with glutathione or influence its metabolism, can also enhance GGT6 activity. Sulfasalazine, by affecting glutathione levels, and Oltipraz, by inducing phase II detoxification enzymes, can create conditions that necessitate increased GGT6 activity. Additionally, compounds like Alpha-Lipoic Acid, Curcumin, Selenium, and Vitamin C, which influence the cellular redox status and antioxidant pathways, can indirectly augment the role of GGT6 in maintaining oxidative balance and detoxification.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Glutathione, reduced

70-18-8sc-29094
sc-29094A
10 g
1 kg
$82.00
$2091.00
8
(2)

As the substrate for GGT enzymes, increased levels of GSH could enhance GGT6 activity in glutathione metabolism.

N-Acetyl-L-cysteine

616-91-1sc-202232
sc-202232A
sc-202232C
sc-202232B
5 g
25 g
1 kg
100 g
$34.00
$74.00
$270.00
$114.00
34
(1)

A precursor to glutathione, NAC can increase intracellular glutathione levels, potentially enhancing GGT6 activity.

Sulfasalazine

599-79-1sc-204312
sc-204312A
sc-204312B
sc-204312C
1 g
2.5 g
5 g
10 g
$61.00
$77.00
$128.00
$209.00
8
(1)

As a drug that affects glutathione levels, Sulfasalazine might indirectly enhance GGT6 activity in cellular detoxification.

L-Cysteine

52-90-4sc-286072
sc-286072A
sc-286072B
sc-286072C
sc-286072D
25 g
100 g
500 g
5 kg
10 kg
$51.00
$112.00
$449.00
$1151.00
$2178.00
1
(1)

As a key amino acid in glutathione synthesis, increased cysteine levels can indirectly enhance GGT6 activity by boosting glutathione availability.

L-Methionine

63-68-3sc-394076
sc-394076A
sc-394076B
sc-394076C
sc-394076D
sc-394076E
25 g
100 g
250 g
1 kg
5 kg
10 kg
$34.00
$37.00
$57.00
$151.00
$577.00
$1103.00
(0)

Methionine, involved in glutathione synthesis, can indirectly influence GGT6 activity through its role in glutathione metabolism.

α-Lipoic Acid

1077-28-7sc-202032
sc-202032A
sc-202032B
sc-202032C
sc-202032D
5 g
10 g
250 g
500 g
1 kg
$69.00
$122.00
$212.00
$380.00
$716.00
3
(1)

As an antioxidant, Alpha-Lipoic Acid can influence cellular redox status, potentially enhancing GGT6 activity in maintaining oxidative balance.

Oltipraz

64224-21-1sc-205777
sc-205777A
500 mg
1 g
$286.00
$622.00
(1)

Oltipraz induces phase II detoxification enzymes, including GGT, potentially enhancing GGT6 activity in detoxification pathways.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

Curcumin can modulate glutathione levels and oxidative stress response, potentially influencing GGT6 activity.

Selenium

7782-49-2sc-250973
50 g
$62.00
1
(1)

Selenium is important for glutathione metabolism. Adequate selenium levels can indirectly enhance GGT6 activity.

L-Ascorbic acid, free acid

50-81-7sc-202686
100 g
$46.00
5
(1)

Vitamin C can regenerate glutathione from its oxidized form, potentially increasing the functional demand for GGT6 in glutathione metabolism.