GFRA (GDNF family receptor alpha) Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PD 158780 solution | 171179-06-9 | sc-202758 | 500 µg | $159.00 | ||
A tyrosine kinase inhibitor that can disrupt downstream signaling of GFRα receptors. | ||||||
K-252a | 99533-80-9 | sc-200517 sc-200517B sc-200517A | 100 µg 500 µg 1 mg | $126.00 $210.00 $488.00 | 19 | |
A kinase inhibitor known to block the activity of neurotrophin receptors and could potentially inhibit GFRα-associated kinase activity. | ||||||
Lapatinib ditosylate | 388082-78-8 | sc-202205B sc-202205 sc-202205A | 5 mg 10 mg 25 mg | $48.00 $75.00 $115.00 | 15 | |
While primarily targeting EGFR and HER2, it may have off-target effects on RET kinase, which is often associated with GFRα receptors. | ||||||
BIBF1120 | 656247-17-5 | sc-364433 sc-364433A | 5 mg 10 mg | $180.00 $315.00 | 2 | |
A tyrosine kinase inhibitor that could indirectly affect GFRα signaling pathways. | ||||||
Sorafenib | 284461-73-0 | sc-220125 sc-220125A sc-220125B | 5 mg 50 mg 500 mg | $56.00 $260.00 $416.00 | 129 | |
Another tyrosine kinase inhibitor with potential off-target effects that could disrupt GFRα-related signaling. | ||||||
SU 5402 | 215543-92-3 | sc-204308 sc-204308A | 1 mg 5 mg | $62.00 $96.00 | 36 | |
A compound known to inhibit fibroblast growth factor receptors (FGFRs) and could potentially have effects on GFRα signaling pathways. | ||||||
Imatinib | 152459-95-5 | sc-267106 sc-267106A sc-267106B | 10 mg 100 mg 1 g | $25.00 $117.00 $209.00 | 27 | |
Primarily targets BCR-ABL, c-KIT, and PDGFR, but may also have effects on GFRα signaling due to its broad kinase inhibition profile. | ||||||