Date published: 2026-5-6

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General Crosslinkers

Santa Cruz Biotechnology now offers a broad range of crosslinkers for use in various applications. Crosslinkers are versatile chemical agents that can form covalent bonds between different molecules, thus linking them together. These compounds are crucial in scientific research for stabilizing the structure of proteins, nucleic acids, and other biomolecules, allowing for more accurate studies of their functions and interactions. By creating crosslinked networks, researchers can investigate the three-dimensional structure of macromolecules, study the dynamics of complex biological systems, and enhance the durability and functionality of biomaterials. In material science, crosslinkers are used to develop polymers with improved mechanical properties, such as increased strength and resistance to solvents and heat. Additionally, they play a vital role in developing and optimizing new materials, adhesives, coatings, and composites. The ability of crosslinkers to create strong, stable bonds has also been utilized in various biochemical techniques, such as immunoprecipitation, chromatography, and mass spectrometry, where they help in isolating and identifying specific molecules from complex mixtures. Santa Cruz Biotechnology provides a wide selection of crosslinkers, each with unique properties tailored for specific research needs, ensuring researchers have the tools necessary for their studies. View detailed information on our available crosslinkers by clicking on the product name.

Items 221 to 230 of 343 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

N-Boc-p-phenylenediamine

71026-66-9sc-253108
5 g
$162.00
(0)

N-Boc-p-phenylenediamine serves as an effective crosslinker due to its ability to form stable covalent bonds through its amine groups. The presence of the Boc (tert-butyloxycarbonyl) protecting group enhances its stability and reactivity, allowing for selective functionalization. Its aromatic structure promotes π-π stacking interactions, which can lead to increased network density in polymer matrices. This compound's unique reactivity and structural features facilitate tailored material properties in various applications.

Bis(3,5-dibromosalicyl) succinate

71337-52-5sc-205228
sc-205228A
sc-205228B
sc-205228C
sc-205228D
sc-205228E
100 mg
500 mg
1 g
5 g
50 g
100 g
$35.00
$121.00
$242.00
$750.00
$6005.00
$10000.00
(0)

Bis(3,5-dibromosalicyl) succinate serves as an effective crosslinker, exhibiting strong reactivity through its multiple bromine substituents, which enhance electrophilic interactions. This compound facilitates the formation of robust networks by promoting covalent bonding between polymer chains, leading to improved mechanical properties. Its unique structural arrangement allows for selective interactions with functional groups, influencing the kinetics of crosslinking reactions and enhancing thermal stability in composite materials.

N-Boc-1,3-propanediamine

75178-96-0sc-255338
1 ml
$126.00
(0)

N-Boc-1,3-propanediamine serves as a versatile crosslinker, characterized by its capacity to engage in robust hydrogen bonding and electrostatic interactions. The presence of the Boc group not only stabilizes the amine functionalities but also enhances the compound's reactivity towards various electrophiles. This enables the formation of diverse crosslinked structures, which can exhibit improved elasticity and resilience, making it suitable for creating complex polymer matrices with tailored properties.

N-Succinimidyloxycarbonylpentyl Methanethiosulfonate

76078-81-4sc-212285
10 mg
$290.00
(0)

N-Succinimidyloxycarbonylpentyl Methanethiosulfonate serves as an effective crosslinker, distinguished by its pentyl chain that enhances hydrophobic interactions. This compound features a methanethiosulfonate group, which selectively reacts with thiols to form stable thioether linkages. Its unique structure allows for tailored crosslinking density, influencing the mechanical properties of the resulting networks. The compound's reactivity profile supports rapid covalent bond formation, making it suitable for various applications.

N-Z-Ethanolamine

77987-49-6sc-255365
5 g
$21.00
(0)

N-Z-Ethanolamine functions as an effective crosslinker, distinguished by its dual functional groups that enable diverse bonding interactions. The presence of both hydroxyl and amine groups facilitates hydrogen bonding and nucleophilic attack, promoting intricate network formation. This compound exhibits a unique ability to enhance the viscosity and stability of polymer systems, while its hydrophilic nature contributes to improved adhesion properties, making it suitable for a range of applications in material science.

N-(3-Hydroxypropyl)trifluoroacetamide

78008-15-8sc-253067
500 mg
$151.00
(0)

N-(3-Hydroxypropyl)trifluoroacetamide functions as an effective crosslinker, distinguished by its trifluoroacetamide group that imparts strong electrophilic reactivity. The hydroxypropyl segment facilitates enhanced intermolecular interactions, promoting extensive hydrogen bonding and contributing to the stability of crosslinked structures. This compound exhibits tailored reactivity profiles, allowing for controlled crosslinking kinetics, which can optimize the mechanical properties and thermal stability of polymeric systems. Its unique molecular architecture enables precise manipulation of network density, enhancing material performance.

N-Z-1,6-hexanediamine hydrochloride

78618-06-1sc-253133
1 g
$115.00
(0)

N-Z-1,6-hexanediamine hydrochloride acts as a versatile crosslinker, characterized by its unique chain length that allows for flexible spatial arrangements in polymer networks. The presence of multiple amine groups enables extensive hydrogen bonding and ionic interactions, enhancing network density. Its reactivity is influenced by steric factors, which can affect reaction kinetics and the formation of crosslinked structures, ultimately improving the durability and resilience of composite materials.

4-(2-Chloropropionyl)phenylacetic acid

84098-73-7sc-252079
1 g
$154.00
(0)

4-(2-Chloropropionyl)phenylacetic acid acts as a versatile crosslinker, leveraging its electrophilic carbonyl group to engage in nucleophilic addition reactions with amines and alcohols. The presence of the chloropropionyl moiety enhances its reactivity, enabling rapid crosslinking under mild conditions. Its aromatic backbone contributes to strong π-π interactions, promoting enhanced mechanical strength and thermal stability in polymer networks. This compound's unique reactivity profile allows for the customization of material properties in diverse applications.

N-Boc-4-isothiocyanatoaniline

89631-75-4sc-236015
500 mg
$202.00
(0)

N-Boc-4-isothiocyanatoaniline functions as an effective crosslinker, distinguished by its isothiocyanate group that engages in nucleophilic addition reactions. This reactivity allows for the formation of stable thiourea linkages with amines, enhancing network integrity. The presence of the Boc protecting group provides stability during synthesis, while its eventual removal facilitates further functionalization. This compound's unique interaction pathways enable precise control over crosslinking density, influencing the mechanical and thermal properties of polymeric materials.

3-(4-Hydroxymethylphenoxy)propionic acid

101366-61-4sc-251913
1 g
$74.00
(0)

3-(4-Hydroxymethylphenoxy)propionic acid serves as an effective crosslinker, distinguished by its phenolic hydroxyl group that enhances hydrogen bonding interactions. This compound promotes the formation of robust ester linkages, facilitating the development of complex polymeric structures. Its reactivity with various functional groups allows for tailored reaction pathways, enabling precise control over network density and mechanical characteristics, ultimately leading to materials with improved stability and performance.