Date published: 2026-5-6

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General Crosslinkers

Santa Cruz Biotechnology now offers a broad range of crosslinkers for use in various applications. Crosslinkers are versatile chemical agents that can form covalent bonds between different molecules, thus linking them together. These compounds are crucial in scientific research for stabilizing the structure of proteins, nucleic acids, and other biomolecules, allowing for more accurate studies of their functions and interactions. By creating crosslinked networks, researchers can investigate the three-dimensional structure of macromolecules, study the dynamics of complex biological systems, and enhance the durability and functionality of biomaterials. In material science, crosslinkers are used to develop polymers with improved mechanical properties, such as increased strength and resistance to solvents and heat. Additionally, they play a vital role in developing and optimizing new materials, adhesives, coatings, and composites. The ability of crosslinkers to create strong, stable bonds has also been utilized in various biochemical techniques, such as immunoprecipitation, chromatography, and mass spectrometry, where they help in isolating and identifying specific molecules from complex mixtures. Santa Cruz Biotechnology provides a wide selection of crosslinkers, each with unique properties tailored for specific research needs, ensuring researchers have the tools necessary for their studies. View detailed information on our available crosslinkers by clicking on the product name.

Items 231 to 240 of 343 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Sulphosuccinimidyl 6-(4′-azido-2′-nitrophenylamino)hexanoate

102568-43-4sc-355990
100 mg
$306.00
(0)

Sulphosuccinimidyl 6-(4'-azido-2'-nitrophenylamino)hexanoate is a versatile crosslinker featuring an azido group that engages in specific interactions with nucleophiles, promoting targeted conjugation. Its unique nitrophenyl moiety enhances reactivity, allowing for efficient formation of covalent bonds under mild conditions. This compound's ability to create complex three-dimensional structures enables the development of materials with customized mechanical and thermal properties, making it suitable for diverse applications in material science.

2-(Fmoc-amino)ethanol

105496-31-9sc-229861
1 g
$39.00
(0)

2-(Fmoc-amino)ethanol functions as an effective crosslinker, distinguished by its ability to engage in selective interactions with various functional groups. The presence of the Fmoc protecting group enhances its stability and reactivity, facilitating the formation of robust linkages in polymer matrices. Its unique structure promotes specific hydrogen bonding and steric effects, allowing for tailored crosslinking pathways that can optimize the mechanical integrity and resilience of the resulting materials.

(p-Azidosalicylamido)ethyl-1,3′-dithiopropionic Acid

107426-70-0sc-212501
10 mg
$300.00
(0)

(p-Azidosalicylamido)ethyl-1,3'-dithiopropionic Acid serves as a versatile crosslinker, characterized by its unique azide functionality that enables efficient click chemistry reactions. This compound exhibits strong reactivity with alkyne groups, facilitating the formation of stable covalent bonds. Its dithiopropionic structure enhances solubility in various solvents, promoting uniform distribution in polymer matrices. Additionally, the compound's ability to form crosslinked networks contributes to improved mechanical properties and thermal stability in composite materials.

N-Boc-N-methylethylenediamine

121492-06-6sc-255348
1 ml
$316.00
(0)

N-Boc-N-methylethylenediamine acts as an effective crosslinker, distinguished by its ability to form stable imine bonds through condensation reactions. The Boc (tert-butyloxycarbonyl) protecting group enhances its stability and reactivity, allowing for selective interactions with amines and other nucleophiles. This compound's unique structure facilitates the formation of intricate polymer architectures, promoting tailored mechanical properties and thermal stability in crosslinked networks.

N-Succinimidyl 6-[[4-(Maleimidomethyl)cyclohexyl]carboxamido] Caproate

125559-00-4sc-219227
10 mg
$300.00
(0)

N-Succinimidyl 6-[[4-(Maleimidomethyl)cyclohexyl]carboxamido] Caproate serves as a versatile crosslinker, characterized by its reactive succinimidyl ester that facilitates efficient amine coupling. The presence of the maleimide moiety allows for selective thiol interactions, promoting targeted crosslinking. Its elongated caproate chain enhances flexibility, improving spatial arrangement in polymer matrices, while the cyclohexyl group contributes to unique steric properties, optimizing reaction kinetics and stability in diverse conditions.

N-(2-[(t-Boc)amino]ethyl Maleimide

134272-63-2sc-218906
500 mg
$380.00
(0)

N-(2-[(t-Boc)amino]ethyl Maleimide serves as an effective crosslinker, distinguished by its t-Boc protective group that enhances stability and reactivity. This compound engages in thiol-maleimide click chemistry, enabling precise and efficient crosslinking under mild conditions. Its unique structure promotes selective interactions with thiol groups, facilitating the formation of resilient networks. The presence of the maleimide moiety also contributes to its compatibility with diverse polymer matrices, enhancing material properties.

4-(4-Hydroxymethyl-3-methoxyphenoxy)butyric acid

136849-75-7sc-254565
1 g
$208.00
(0)

4-(4-Hydroxymethyl-3-methoxyphenoxy)butyric acid functions as an effective crosslinker, distinguished by its phenolic structure that facilitates hydrogen bonding and π-π stacking interactions. This compound promotes the formation of robust three-dimensional networks, enhancing the structural integrity of polymers. Its reactivity with various functional groups allows for tailored modifications, optimizing the kinetics of crosslinking and improving the overall performance of composite materials.

N-Boc-2-isothiocyanatoethylamine

137743-46-5sc-250448
500 mg
$145.00
(0)

N-Boc-2-isothiocyanatoethylamine acts as an effective crosslinker, distinguished by its capacity to engage in rapid thiourea bond formation via nucleophilic substitution. The isothiocyanate group facilitates targeted interactions with amine functionalities, enabling the creation of customized polymer architectures. The presence of the Boc protecting group enhances stability during synthesis while allowing for further functionalization. This compound's reactivity and structural versatility contribute to the optimization of material properties, including elasticity and chemical resistance.

N-Boc-iminodipropionic acid

143766-89-6sc-228690
500 mg
$216.00
(0)

N-Boc-iminodipropionic acid serves as an effective crosslinker due to its ability to form stable covalent bonds through its reactive functional groups. The presence of the Boc protecting group enhances its solubility and stability, allowing for controlled reaction kinetics. Its unique structure promotes specific interactions with amine and carboxylic acid functionalities, facilitating the formation of robust networks in polymer matrices. This compound's versatility in modifying physical properties makes it a valuable component in material science.

4-[(2,4-Dimethoxyphenyl)(Fmoc-amino)methyl]phenoxyacetic acid

145069-56-3sc-226455
5 g
$638.00
(0)

4-[(2,4-Dimethoxyphenyl)(Fmoc-amino)methyl]phenoxyacetic acid serves as an innovative crosslinker, distinguished by its ability to engage in selective hydrogen bonding and π-π stacking interactions. This compound facilitates the formation of robust networks through its phenoxy and amino functionalities, promoting enhanced structural integrity. Its unique steric properties influence reaction kinetics, allowing for controlled crosslinking under mild conditions, which can lead to tailored material characteristics.