Date published: 2025-9-15

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General Crosslinkers

Santa Cruz Biotechnology now offers a broad range of crosslinkers for use in various applications. Crosslinkers are versatile chemical agents that can form covalent bonds between different molecules, thus linking them together. These compounds are crucial in scientific research for stabilizing the structure of proteins, nucleic acids, and other biomolecules, allowing for more accurate studies of their functions and interactions. By creating crosslinked networks, researchers can investigate the three-dimensional structure of macromolecules, study the dynamics of complex biological systems, and enhance the durability and functionality of biomaterials. In material science, crosslinkers are used to develop polymers with improved mechanical properties, such as increased strength and resistance to solvents and heat. Additionally, they play a vital role in developing and optimizing new materials, adhesives, coatings, and composites. The ability of crosslinkers to create strong, stable bonds has also been utilized in various biochemical techniques, such as immunoprecipitation, chromatography, and mass spectrometry, where they help in isolating and identifying specific molecules from complex mixtures. Santa Cruz Biotechnology provides a wide selection of crosslinkers, each with unique properties tailored for specific research needs, ensuring researchers have the tools necessary for their studies. View detailed information on our available crosslinkers by clicking on the product name.

Items 241 to 250 of 345 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

N-Boc-iminodipropionic acid

143766-89-6sc-228690
500 mg
$216.00
(0)

N-Boc-iminodipropionic acid serves as an effective crosslinker due to its ability to form stable covalent bonds through its reactive functional groups. The presence of the Boc protecting group enhances its solubility and stability, allowing for controlled reaction kinetics. Its unique structure promotes specific interactions with amine and carboxylic acid functionalities, facilitating the formation of robust networks in polymer matrices. This compound's versatility in modifying physical properties makes it a valuable component in material science.

4-[(2,4-Dimethoxyphenyl)(Fmoc-amino)methyl]phenoxyacetic acid

145069-56-3sc-226455
5 g
$638.00
(0)

4-[(2,4-Dimethoxyphenyl)(Fmoc-amino)methyl]phenoxyacetic acid serves as an innovative crosslinker, distinguished by its ability to engage in selective hydrogen bonding and π-π stacking interactions. This compound facilitates the formation of robust networks through its phenoxy and amino functionalities, promoting enhanced structural integrity. Its unique steric properties influence reaction kinetics, allowing for controlled crosslinking under mild conditions, which can lead to tailored material characteristics.

6-(Allyloxycarbonylamino)-1-hexanol

146292-92-4sc-239085
1 g
$78.00
(0)

6-(Allyloxycarbonylamino)-1-hexanol functions as an effective crosslinker, distinguished by its unique structural features that promote strong intermolecular interactions. The presence of the allyloxycarbonyl moiety enhances its reactivity, enabling efficient formation of crosslinked networks through nucleophilic attack mechanisms. Its hydrophilic nature contributes to improved solubility in polar solvents, facilitating uniform dispersion in polymer matrices. This compound's ability to fine-tune crosslinking density allows for tailored mechanical properties and enhanced material performance.

1,1′-Bis(dicyclohexylphosphino)ferrocene

146960-90-9sc-222770
sc-222770A
250 mg
1 g
$45.00
$143.00
(0)

1,1'-Bis(dicyclohexylphosphino)ferrocene serves as an effective crosslinker, showcasing remarkable coordination chemistry due to its bidentate phosphine ligands. The ferrocene backbone imparts unique electronic properties, facilitating strong metal-ligand interactions. Its sterically bulky dicyclohexyl groups enhance selectivity in crosslinking reactions, while the compound's robust stability under various conditions allows for controlled polymerization processes, optimizing material properties in diverse applications.

(+/-)-trans-1,2-Bis(chloroacetamido)cyclohexane

150576-46-8sc-213079
250 mg
$300.00
(0)

(+/-)-trans-1,2-Bis(chloroacetamido)cyclohexane serves as a versatile crosslinker, characterized by its ability to form robust amide bonds through nucleophilic attack on its chloroacetamido groups. This compound exhibits a unique conformational flexibility due to its cyclohexane backbone, allowing for tailored spatial arrangements in polymer networks. Its reactivity is influenced by steric factors, enabling selective crosslinking under mild conditions, which enhances the mechanical properties and thermal stability of the resulting materials.

3-(Bromomethyl)benzoic acid N-succinimidylester

155863-35-7sc-225878
1 g
$229.00
(0)

3-(Bromomethyl)benzoic acid N-succinimidylester serves as a versatile crosslinker, characterized by its bromomethyl and succinimidyl functionalities that enable robust covalent bonding. The bromomethyl group enhances electrophilic character, facilitating rapid reaction with nucleophiles, while the succinimidyl ester promotes selective coupling with amines. This compound exhibits unique reactivity patterns, allowing for fine-tuning of crosslinking density and network formation, ultimately influencing the mechanical and thermal properties of the resulting materials. Its distinct molecular design supports diverse applications in polymer chemistry, enabling tailored material characteristics.

2-Maleimidoethyl mesylate

155863-36-8sc-288183
1 g
$143.00
(0)

2-Maleimidoethyl mesylate serves as an effective crosslinker, characterized by its maleimide moiety that engages in thiol-ene click reactions, promoting robust covalent bonding. The mesylate group enhances electrophilicity, facilitating rapid reaction kinetics with nucleophiles. This compound's unique ability to form stable crosslinked networks is attributed to its dual reactivity, allowing for precise control over polymer architecture and mechanical properties in various applications.

S-[2-(4-Azidosalicylamido)ethylthio]-2-thiopyridine

164575-82-0sc-212808
10 mg
$367.00
(0)

S-[2-(4-Azidosalicylamido)ethylthio]-2-thiopyridine serves as an effective crosslinker due to its azide functional group, which facilitates click chemistry reactions. The compound's thiopyridine moiety enhances its ability to form covalent bonds with various substrates, promoting robust network formation. Its unique steric and electronic properties allow for selective interactions, leading to tailored material properties and improved mechanical strength in polymer matrices.

Sulfo-N-succinimidyl 6-[3-(2-Pyridyldithio)propionamido] Hexanoate, Sodium Salt

169751-10-4sc-208407
5 mg
$340.00
(0)

Sulfo-N-succinimidyl 6-[3-(2-Pyridyldithio)propionamido] Hexanoate, Sodium Salt is a specialized crosslinker that features a pyridyldithio moiety, enabling disulfide bond formation under reducing conditions. This compound exhibits high specificity in targeting amine groups, facilitating precise conjugation in complex biomolecular systems. Its unique structure promotes efficient crosslinking kinetics, resulting in stable networks with enhanced mechanical integrity and tailored functional properties.

S-[2-(Iodo-4-Azidosalicylamido)ethylthio]-2-thiopyridine

175093-14-8sc-212809
5 mg
$360.00
(0)

S-[2-(Iodo-4-Azidosalicylamido)ethylthio]-2-thiopyridine is a versatile crosslinker characterized by its iodo and azido groups, which enable diverse coupling reactions. The presence of the thiopyridine ring contributes to its reactivity, allowing for efficient formation of stable linkages. This compound exhibits unique solubility and compatibility with various solvents, enhancing its utility in creating complex polymer architectures. Its distinct electronic properties facilitate specific interactions, optimizing crosslink density and material performance.