Date published: 2026-5-6

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General Crosslinkers

Santa Cruz Biotechnology now offers a broad range of crosslinkers for use in various applications. Crosslinkers are versatile chemical agents that can form covalent bonds between different molecules, thus linking them together. These compounds are crucial in scientific research for stabilizing the structure of proteins, nucleic acids, and other biomolecules, allowing for more accurate studies of their functions and interactions. By creating crosslinked networks, researchers can investigate the three-dimensional structure of macromolecules, study the dynamics of complex biological systems, and enhance the durability and functionality of biomaterials. In material science, crosslinkers are used to develop polymers with improved mechanical properties, such as increased strength and resistance to solvents and heat. Additionally, they play a vital role in developing and optimizing new materials, adhesives, coatings, and composites. The ability of crosslinkers to create strong, stable bonds has also been utilized in various biochemical techniques, such as immunoprecipitation, chromatography, and mass spectrometry, where they help in isolating and identifying specific molecules from complex mixtures. Santa Cruz Biotechnology provides a wide selection of crosslinkers, each with unique properties tailored for specific research needs, ensuring researchers have the tools necessary for their studies. View detailed information on our available crosslinkers by clicking on the product name.

Items 211 to 220 of 343 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

3-N-Maleimidobenzoic Acid N-Succinimidyl Ester

58626-38-3sc-209654
250 mg
$300.00
(0)

3-N-Maleimidobenzoic Acid N-Succinimidyl Ester is a versatile crosslinker characterized by its maleimide and succinimidyl functionalities. This compound exhibits selective reactivity towards thiol groups, enabling the formation of stable thioether bonds. Its unique structure allows for rapid reaction kinetics, facilitating efficient crosslinking in diverse systems. The presence of the aromatic ring enhances hydrophobic interactions, contributing to the stability and integrity of crosslinked networks.

3-(Boc-amino)-1-propanol

58885-58-8sc-256410
50 ml
$232.00
(0)

3-(Boc-amino)-1-propanol serves as a versatile crosslinker, characterized by its ability to form stable amine linkages through nucleophilic attack. The presence of the Boc (tert-butyloxycarbonyl) protecting group enhances its stability and reactivity, facilitating selective crosslinking in polymer matrices. This compound exhibits unique solubility properties, allowing for effective dispersion in various solvents, which can influence the kinetics of crosslinking reactions and the resulting material characteristics.

6-(4-Azido-2-nitrophenylamino)hexanoic acid N-hydroxysuccinimide ester

64309-05-3sc-256960
50 mg
$516.00
(0)

6-(4-Azido-2-nitrophenylamino)hexanoic acid N-hydroxysuccinimide ester serves as a versatile crosslinker, characterized by its azide functionality that enables selective click chemistry. This compound exhibits unique photochemical properties, allowing for light-triggered reactions that enhance spatial control in polymer networks. Its N-hydroxysuccinimide ester moiety facilitates efficient amine coupling, promoting robust linkages in diverse environments, thus broadening its applicability in material synthesis and bioconjugation.

1-Methanesulfonyl-11-hydroxy-3,6,9-trioxaundecane

65883-12-7sc-213346
250 mg
$300.00
(0)

1-Methanesulfonyl-11-hydroxy-3,6,9-trioxaundecane serves as an effective crosslinker due to its unique trioxaundecane backbone, which facilitates multiple hydrogen bonding interactions. This compound's sulfonyl group enhances its electrophilic character, allowing for efficient reactions with nucleophilic sites in polymers. Its ability to create robust three-dimensional networks contributes to improved thermal stability and mechanical integrity, making it suitable for diverse polymeric applications.

N-Boc-1,6-hexanediamine hydrochloride

65915-94-8sc-253100
1 g
$57.00
(0)

N-Boc-1,6-hexanediamine hydrochloride serves as a versatile crosslinker, characterized by its bifunctional amine groups that facilitate diverse bonding interactions. The presence of the Boc (tert-butyloxycarbonyl) protecting group enhances stability during processing, while the amine functionality enables rapid formation of imine linkages. This compound's ability to create intricate networks significantly influences the mechanical properties and thermal resistance of polymer matrices, allowing for customized material performance.

Phenacyl 4-(bromomethyl)phenylacetate

66270-97-1sc-253257
5 g
$113.00
(0)

Phenacyl 4-(bromomethyl)phenylacetate acts as an effective crosslinker, distinguished by its electrophilic bromomethyl group that readily engages in nucleophilic substitution reactions. This reactivity promotes the formation of robust covalent bonds with nucleophiles, enhancing the structural integrity of polymer systems. Its unique aromatic structure contributes to increased thermal stability and mechanical strength, enabling tailored material properties through controlled crosslinking pathways.

N-(Allyloxycarbonyl)ethanolamine

66471-00-9sc-253078
250 mg
$250.00
(0)

N-(Allyloxycarbonyl)ethanolamine serves as a versatile crosslinker, characterized by its ability to engage in dynamic covalent bonding. The allyloxycarbonyl group enhances its electrophilic character, promoting rapid reaction kinetics with nucleophiles. This compound exhibits a balance of hydrophilicity and hydrophobicity, which aids in compatibility with various polymer systems. Its unique reactivity profile allows for the precise modulation of crosslinking density, resulting in customized material properties and improved structural integrity.

di-Boc-cystamine

67385-10-8sc-252671
5 g
$127.00
(0)

di-Boc-cystamine acts as a robust crosslinker, characterized by its dual thiol groups that enable the formation of disulfide bonds, contributing to the stability of polymer networks. The Boc protecting groups enhance its solubility and reactivity, allowing for controlled crosslinking under specific conditions. Its unique molecular structure facilitates diverse interactions, including hydrophobic and electrostatic forces, which can significantly influence the mechanical properties and thermal stability of the resulting materials.

Allyl(4-methoxyphenyl)dimethylsilane

68469-60-3sc-233835
1 ml
$25.00
(0)

Allyl(4-methoxyphenyl)dimethylsilane serves as an effective crosslinker, characterized by its unique silane functionality that promotes robust covalent bonding in polymer matrices. The presence of the methoxy group enhances its reactivity, facilitating selective interactions with hydroxyl and amine groups. This compound exhibits favorable reaction kinetics, enabling rapid crosslinking under mild conditions. Its hydrophobic nature contributes to improved thermal stability and mechanical properties in composite materials.

N-Boc-m-phenylenediamine

68621-88-5sc-236022
5 g
$199.00
(0)

N-Boc-m-phenylenediamine functions as a versatile crosslinker, distinguished by its ability to form stable imine bonds through its amine groups. The Boc (tert-butyloxycarbonyl) protecting group enhances its stability and reactivity, allowing for controlled crosslinking in various polymer systems. Its unique molecular structure promotes specific interactions with electrophiles, leading to tailored network formation. Additionally, its solubility in organic solvents aids in uniform dispersion within matrices, optimizing mechanical performance.