Date published: 2026-5-6

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General Crosslinkers

Santa Cruz Biotechnology now offers a broad range of crosslinkers for use in various applications. Crosslinkers are versatile chemical agents that can form covalent bonds between different molecules, thus linking them together. These compounds are crucial in scientific research for stabilizing the structure of proteins, nucleic acids, and other biomolecules, allowing for more accurate studies of their functions and interactions. By creating crosslinked networks, researchers can investigate the three-dimensional structure of macromolecules, study the dynamics of complex biological systems, and enhance the durability and functionality of biomaterials. In material science, crosslinkers are used to develop polymers with improved mechanical properties, such as increased strength and resistance to solvents and heat. Additionally, they play a vital role in developing and optimizing new materials, adhesives, coatings, and composites. The ability of crosslinkers to create strong, stable bonds has also been utilized in various biochemical techniques, such as immunoprecipitation, chromatography, and mass spectrometry, where they help in isolating and identifying specific molecules from complex mixtures. Santa Cruz Biotechnology provides a wide selection of crosslinkers, each with unique properties tailored for specific research needs, ensuring researchers have the tools necessary for their studies. View detailed information on our available crosslinkers by clicking on the product name.

Items 201 to 210 of 343 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

8-Bromo-1-octanol

50816-19-8sc-257015
1 g
$53.00
(0)

8-Bromo-1-octanol acts as an effective crosslinker, distinguished by its ability to form covalent bonds through its bromine substituent, which facilitates nucleophilic attack. This compound promotes unique molecular interactions, enhancing network formation in polymer systems. Its hydrophobic octanol chain contributes to phase separation and compatibility in various matrices, while the bromine atom can participate in radical reactions, further diversifying crosslinking pathways and improving material stability.

t-Boc-aminocaproic-N-hydroxysuccinimide

51513-80-5sc-212985
25 mg
$380.00
(0)

t-Boc-aminocaproic-N-hydroxysuccinimide serves as a versatile crosslinker, characterized by its ability to facilitate amide bond formation through its N-hydroxysuccinimide group. This compound exhibits a unique reactivity profile, allowing for selective coupling with primary amines, which enhances the specificity of crosslinking in complex systems. Its t-Boc protecting group provides stability during storage and handling, while enabling deprotection under mild conditions, thus allowing for controlled release and functionalization in diverse applications.

N-Boc-cadaverine

51644-96-3sc-253102
1 ml
$121.00
(0)

N-Boc-cadaverine is a versatile crosslinker characterized by its ability to form dynamic covalent bonds through its primary amine functionalities. The presence of the Boc protecting group not only stabilizes the molecule but also facilitates selective reactivity, enabling tailored crosslinking strategies. Its unique molecular architecture allows for the creation of intricate three-dimensional networks, enhancing the thermal and mechanical resilience of polymer systems while promoting specific interactions that can fine-tune material properties.

1,11-Bis(methanesulfonyloxy)-3,6,9-trioxandecane

55400-73-2sc-208714
1 g
$320.00
(0)

1,11-Bis(methanesulfonyloxy)-3,6,9-trioxandecane serves as an effective crosslinker, exhibiting remarkable reactivity through its sulfonate esters. The compound's unique structure enables rapid formation of covalent bonds, facilitating the creation of robust polymer networks. Its ability to engage in multiple crosslinking mechanisms enhances the thermal stability and mechanical strength of materials, while its hydrophilic nature promotes compatibility with various polymer matrices, leading to tailored material properties.

6-Maleimidocaproic Acid

55750-53-3sc-357915
250 mg
$180.00
(0)

6-Maleimidocaproic Acid is a specialized crosslinker known for its maleimide group, which selectively reacts with thiol-containing compounds, forming stable thioether bonds. This reactivity allows for precise control over polymer architecture and protein conjugation. The compound's flexible carbon chain enhances solubility and facilitates steric accessibility, promoting efficient crosslinking kinetics. Its unique properties make it a valuable tool for creating complex biomolecular structures and tailored materials.

N-(10-Carboxydecanyl)maleamideic Acid

57079-16-0sc-211947
250 mg
$300.00
(0)

N-(10-Carboxydecanyl)maleamideic Acid serves as a versatile crosslinker, characterized by its ability to form strong covalent bonds through its maleamide functionality. This compound exhibits unique reactivity with nucleophiles, enabling efficient crosslinking in polymer matrices. Its long aliphatic chain enhances hydrophobic interactions, contributing to improved material flexibility and durability. The distinct carboxylic acid group also facilitates ionic interactions, further optimizing network formation and stability.

N-Succinimidyl 3-(Bromoacetamido)propionate

57159-62-3sc-212276
10 mg
$360.00
(0)

N-Succinimidyl 3-(Bromoacetamido)propionate serves as an effective crosslinker, characterized by its bromoacetamido moiety that engages in nucleophilic substitution reactions. This feature allows for selective targeting of amine groups, resulting in stable covalent linkages. The compound's unique reactivity profile promotes rapid crosslinking, even in complex biological environments. Its compatibility with various solvents enhances its utility across diverse experimental conditions, making it a valuable tool for creating intricate molecular networks.

N-(t-Boc)ethylenediamine

57260-73-8sc-218982
500 mg
$152.00
(0)

N-(t-Boc)ethylenediamine acts as a versatile crosslinker, characterized by its bulky t-Boc protecting group that enhances steric hindrance, influencing reaction pathways. This compound engages in robust amine-based interactions, facilitating the formation of stable networks through dynamic covalent bonding. Its unique structure allows for tunable reactivity, enabling controlled crosslinking rates and improved compatibility with various polymer systems, ultimately enhancing material performance.

1,14-Dibromo-3,6,9,12-tetraoxatetradecane

57602-02-5sc-208717
25 mg
$330.00
(0)

1,14-Dibromo-3,6,9,12-tetraoxatetradecane serves as an effective crosslinker, distinguished by its bromine substituents that promote halogen bonding interactions. This compound's tetraoxatetradecane structure enhances its ability to form robust networks through multiple reaction pathways, including radical and ionic mechanisms. Its unique physical properties, such as increased thermal stability and compatibility with diverse polymer matrices, make it ideal for creating durable materials with tailored mechanical characteristics.

Bis[2-(succinimidooxycarbonyloxy)ethyl] Sulfone

57683-72-4sc-210948
25 mg
$306.00
(0)

Bis[2-(succinimidooxycarbonyloxy)ethyl] Sulfone serves as an effective crosslinker, characterized by its ability to form robust covalent bonds through nucleophilic attack on electrophilic sites. Its unique sulfone moiety enhances polarity, facilitating strong interactions with various substrates. The compound's flexible ether linkages allow for dynamic conformational changes, optimizing crosslink density and network formation. This versatility in bonding pathways contributes to tailored mechanical properties and thermal stability in polymer matrices.