Date published: 2026-5-6

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General Crosslinkers

Santa Cruz Biotechnology now offers a broad range of crosslinkers for use in various applications. Crosslinkers are versatile chemical agents that can form covalent bonds between different molecules, thus linking them together. These compounds are crucial in scientific research for stabilizing the structure of proteins, nucleic acids, and other biomolecules, allowing for more accurate studies of their functions and interactions. By creating crosslinked networks, researchers can investigate the three-dimensional structure of macromolecules, study the dynamics of complex biological systems, and enhance the durability and functionality of biomaterials. In material science, crosslinkers are used to develop polymers with improved mechanical properties, such as increased strength and resistance to solvents and heat. Additionally, they play a vital role in developing and optimizing new materials, adhesives, coatings, and composites. The ability of crosslinkers to create strong, stable bonds has also been utilized in various biochemical techniques, such as immunoprecipitation, chromatography, and mass spectrometry, where they help in isolating and identifying specific molecules from complex mixtures. Santa Cruz Biotechnology provides a wide selection of crosslinkers, each with unique properties tailored for specific research needs, ensuring researchers have the tools necessary for their studies. View detailed information on our available crosslinkers by clicking on the product name.

Items 191 to 200 of 343 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

4-(Z-Amino)-1-butanol

17996-13-3sc-254586
1 g
$156.00
(0)

4-(Z-Amino)-1-butanol acts as an effective crosslinker, distinguished by its primary amine functionality that enables nucleophilic attack on electrophilic sites, fostering covalent bond formation. Its unique structure promotes strong intermolecular interactions, enhancing network density. The compound's ability to participate in both hydrogen bonding and amine-epoxy reactions allows for tailored crosslinking pathways, resulting in materials with superior elasticity and resilience under stress.

Tris-(2-methanethiosulfonylethyl)amine

18365-77-0sc-213124
25 mg
$300.00
(0)

Tris-(2-methanethiosulfonylethyl)amine serves as an effective crosslinker, characterized by its unique thiol-reactive groups that facilitate the formation of disulfide bonds. This compound exhibits remarkable selectivity in thiol-ene click reactions, promoting efficient network formation in polymer matrices. Its ability to create robust three-dimensional structures enhances mechanical properties and stability, while its tunable reactivity allows for controlled crosslinking under mild conditions, making it versatile in various applications.

N-Z-Ethylenediamine hydrochloride

18807-71-1sc-250493
sc-250493A
250 mg
1 g
$32.00
$56.00
(0)

N-Z-Ethylenediamine hydrochloride acts as an effective crosslinker, distinguished by its dual amine functionality that facilitates robust network formation through hydrogen bonding and ionic interactions. This compound exhibits rapid reaction kinetics, enabling efficient crosslinking even at ambient temperatures. Its hydrophilic nature enhances compatibility with polar solvents, promoting uniform dispersion in polymer matrices. The presence of chloride ions further influences the crosslinking density, optimizing material properties.

N-Z-1,4-Butanediamine hydrochloride

18807-73-3sc-253131
1 g
$142.00
(0)

N-Z-1,4-Butanediamine hydrochloride serves as an effective crosslinker, facilitating the formation of robust polymer networks through its primary amine groups. These groups engage in nucleophilic reactions with electrophilic sites, promoting strong covalent bonds. The compound's ability to enhance thermal stability and mechanical strength in materials is notable, as it influences the reaction kinetics, leading to tailored properties in the final polymer structure. Its hygroscopic nature also aids in moisture retention, further enhancing material performance.

1-[3-(Dimethylamino)propyl]-3-ethylcarbodiimide methiodide

22572-40-3sc-253879
sc-253879A
sc-253879B
1 g
5 g
25 g
$37.00
$126.00
$550.00
(0)

1-[3-(Dimethylamino)propyl]-3-ethylcarbodiimide methiodide serves as a versatile crosslinker, characterized by its ability to form stable amide bonds through its reactive carbodiimide functionality. This compound promotes efficient coupling reactions by activating carboxylic acids, enhancing the formation of peptide bonds. Its unique steric properties and electron-donating dimethylamino group facilitate selective interactions, optimizing reaction kinetics and improving overall yield in polymerization processes.

Sebacic acid bis(N-succinimidyl) ester

23024-29-5sc-253546
100 mg
$63.00
(0)

Sebacic acid bis(N-succinimidyl) ester acts as a versatile crosslinker, characterized by its ability to form stable amide bonds through its N-succinimidyl groups. This compound exhibits a high degree of reactivity with primary amines, enabling rapid crosslinking and the formation of intricate three-dimensional networks. Its unique structure allows for controlled reaction kinetics, facilitating the design of materials with specific mechanical properties and enhanced durability.

4-(tert-Butoxymethyl)benzoic acid

34224-31-2sc-254577
2.5 g
$486.00
(0)

4-(tert-Butoxymethyl)benzoic acid functions as an effective crosslinker due to its ability to form stable covalent bonds through its carboxylic acid group. The tert-butoxymethyl moiety enhances solubility and steric hindrance, promoting selective reactivity in polymer networks. Its unique structure allows for tailored interactions with functional groups, facilitating controlled crosslinking kinetics and improving mechanical properties in composite materials. This versatility makes it a valuable component in material science applications.

3-(Z-Amino)-1-propanol

34637-22-4sc-238483
25 g
$127.00
(0)

3-(Z-Amino)-1-propanol serves as a versatile crosslinker, characterized by its primary amine functionality that facilitates robust hydrogen bonding and nucleophilic reactivity. This compound promotes the formation of stable covalent bonds through its unique ability to engage in Michael addition and condensation reactions. Its flexible aliphatic chain enhances polymer chain mobility, while the presence of the amino group allows for tailored interactions, enabling the design of intricate network structures with specific mechanical properties.

4′-Hydroxy-2,4-dimethoxybenzophenone

41351-30-8sc-252231
5 g
$49.00
(0)

4'-Hydroxy-2,4-dimethoxybenzophenone acts as an effective crosslinker, distinguished by its ability to engage in photochemical reactions that enhance polymer stability. The presence of hydroxyl and methoxy groups facilitates strong intermolecular interactions, promoting the formation of complex networks. Its unique structure allows for selective UV absorption, which can influence reaction kinetics and improve the durability of crosslinked materials, making it suitable for advanced polymer applications.

N-Succinimidyl Bromoacetate

42014-51-7sc-212278
100 mg
$286.00
(0)

N-Succinimidyl Bromoacetate is a versatile crosslinker known for its ability to form stable covalent bonds through its reactive bromoacetate group. This compound facilitates efficient crosslinking by engaging in nucleophilic attack, allowing for precise modification of biomolecules. Its rapid reaction kinetics enable swift formation of linkages, while its solubility in various organic solvents broadens its applicability in diverse experimental setups, promoting the development of complex molecular architectures.