Date published: 2026-5-6

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General Crosslinkers

Santa Cruz Biotechnology now offers a broad range of crosslinkers for use in various applications. Crosslinkers are versatile chemical agents that can form covalent bonds between different molecules, thus linking them together. These compounds are crucial in scientific research for stabilizing the structure of proteins, nucleic acids, and other biomolecules, allowing for more accurate studies of their functions and interactions. By creating crosslinked networks, researchers can investigate the three-dimensional structure of macromolecules, study the dynamics of complex biological systems, and enhance the durability and functionality of biomaterials. In material science, crosslinkers are used to develop polymers with improved mechanical properties, such as increased strength and resistance to solvents and heat. Additionally, they play a vital role in developing and optimizing new materials, adhesives, coatings, and composites. The ability of crosslinkers to create strong, stable bonds has also been utilized in various biochemical techniques, such as immunoprecipitation, chromatography, and mass spectrometry, where they help in isolating and identifying specific molecules from complex mixtures. Santa Cruz Biotechnology provides a wide selection of crosslinkers, each with unique properties tailored for specific research needs, ensuring researchers have the tools necessary for their studies. View detailed information on our available crosslinkers by clicking on the product name.

Items 181 to 190 of 343 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

N-(4-Bromobutyl)phthalimide

5394-18-3sc-250430
10 g
$90.00
(0)

N-(4-Bromobutyl)phthalimide acts as an effective crosslinker, distinguished by its unique phthalimide moiety that facilitates strong π-π stacking interactions within polymer networks. The bromobutyl group enhances nucleophilic attack, promoting rapid crosslinking kinetics. Its rigid structure contributes to thermal stability, while the potential for multiple reaction sites allows for diverse network architectures. This compound's ability to engage in both covalent and non-covalent interactions makes it a valuable tool in material science.

N-(3-Bromopropyl)phthalimide

5460-29-7sc-250429
sc-250429A
25 g
100 g
$41.00
$117.00
(0)

N-(3-Bromopropyl)phthalimide serves as a versatile crosslinker, characterized by its ability to form robust networks through its phthalimide structure. The presence of the bromopropyl group enhances electrophilic reactivity, enabling efficient formation of covalent bonds with nucleophiles. Its unique spatial arrangement allows for effective steric interactions, promoting tailored polymer properties. Additionally, the compound's reactivity can be finely tuned, facilitating the design of materials with specific mechanical and thermal characteristics.

6-Guanidinohexanoic acid

6659-35-4sc-233589
1 g
$194.00
(0)

6-Guanidinohexanoic acid serves as an effective crosslinker, characterized by its guanidine functional group, which facilitates strong hydrogen bonding and ionic interactions. This enhances the formation of robust networks in polymer matrices. Its unique chain length contributes to flexibility and spatial arrangement, allowing for tailored crosslinking density. The compound's reactivity with various functional groups enables diverse pathways for network development, optimizing material properties.

N-(2-Hydroxyethyl)trifluoroacetamide

6974-29-4sc-253066
25 ml
$196.00
(0)

N-(2-Hydroxyethyl)trifluoroacetamide functions as an effective crosslinker, distinguished by its trifluoroacetamide moiety that enhances reactivity through strong hydrogen bonding and dipole interactions. This compound promotes efficient crosslinking via nucleophilic attack mechanisms, leading to robust polymer networks. Its unique ability to form stable linkages under varying conditions contributes to improved thermal and chemical resistance, making it a valuable component in advanced material formulations.

Diethylene glycol monoallyl ether

15075-50-0sc-227853
5 ml
$544.00
(0)

Diethylene glycol monoallyl ether functions as a versatile crosslinker, characterized by its ability to form stable covalent bonds through its allyl groups. The compound exhibits unique reactivity, enabling rapid polymerization via radical mechanisms. Its hydrophilic nature enhances compatibility with various substrates, promoting effective network formation. Additionally, the ether linkages contribute to flexibility in the resulting materials, allowing for tailored mechanical properties and improved thermal stability in crosslinked systems.

Bis-maleimidomethyl Ether

15209-14-0sc-210928
25 mg
$380.00
(0)

Bis-maleimidomethyl Ether serves as a robust crosslinker, distinguished by its dual maleimide groups that enable efficient covalent bonding with thiol-containing molecules. This compound exhibits a high degree of specificity in its interactions, promoting the formation of stable linkages through a Michael addition mechanism. Its flexible ether linkages enhance solubility and compatibility with various substrates, while its reactivity profile allows for controlled crosslinking under mild conditions, making it suitable for diverse applications.

Ac-HMBA-Linker

15561-46-3sc-291784
sc-291784A
5 g
25 g
$268.00
$800.00
(0)

Ac-HMBA-Linker is a versatile crosslinker known for its ability to facilitate robust covalent bonding through its reactive acid halide functionality. This compound exhibits a unique propensity for forming stable linkages with nucleophilic sites, promoting intricate network structures. Its reaction kinetics are characterized by rapid activation, allowing for efficient crosslinking under mild conditions. Additionally, Ac-HMBA-Linker demonstrates excellent solubility in organic solvents, enhancing its compatibility in diverse chemical environments.

4-(t-Boc-amino)-1-butyl Bromide

164365-88-2sc-206781
100 mg
$247.00
(0)

4-(t-Boc-amino)-1-butyl Bromide serves as an effective crosslinker due to its ability to form stable covalent bonds through nucleophilic substitution reactions. The bulky t-Boc group enhances steric hindrance, promoting selective reactivity with amines and thiols. This compound's unique structure facilitates the formation of robust networks, influencing material properties such as elasticity and tensile strength. Its reactivity profile allows for controlled crosslinking kinetics, enabling tailored polymer architectures.

Bis-(2-methanethiosulfonatoethyl)methylamine

16216-82-3sc-207362
10 mg
$330.00
(0)

Bis-(2-methanethiosulfonatoethyl)methylamine functions as a versatile crosslinker, exhibiting remarkable reactivity through its thiol and sulfonate groups. These functional moieties facilitate the formation of covalent bonds with various substrates, enhancing network stability. Its unique structure promotes selective interactions, enabling tailored crosslinking pathways that influence material properties. The compound's ability to modulate reaction kinetics allows for controlled polymerization, making it suitable for diverse applications in material science.

N-Z-1,3-Propanediamine hydrochloride

17400-34-9sc-253130
1 g
$60.00
(0)

N-Z-1,3-Propanediamine hydrochloride serves as an effective crosslinker due to its ability to form robust covalent bonds through amine functionalities. Its primary amine groups engage in nucleophilic reactions, facilitating the formation of stable networks in polymer matrices. The compound's reactivity is influenced by its protonation state, which modulates its interaction with various substrates. This versatility enhances the mechanical properties and thermal stability of the resulting materials, making it a key player in polymer chemistry.