Date published: 2026-5-6

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General Crosslinkers

Santa Cruz Biotechnology now offers a broad range of crosslinkers for use in various applications. Crosslinkers are versatile chemical agents that can form covalent bonds between different molecules, thus linking them together. These compounds are crucial in scientific research for stabilizing the structure of proteins, nucleic acids, and other biomolecules, allowing for more accurate studies of their functions and interactions. By creating crosslinked networks, researchers can investigate the three-dimensional structure of macromolecules, study the dynamics of complex biological systems, and enhance the durability and functionality of biomaterials. In material science, crosslinkers are used to develop polymers with improved mechanical properties, such as increased strength and resistance to solvents and heat. Additionally, they play a vital role in developing and optimizing new materials, adhesives, coatings, and composites. The ability of crosslinkers to create strong, stable bonds has also been utilized in various biochemical techniques, such as immunoprecipitation, chromatography, and mass spectrometry, where they help in isolating and identifying specific molecules from complex mixtures. Santa Cruz Biotechnology provides a wide selection of crosslinkers, each with unique properties tailored for specific research needs, ensuring researchers have the tools necessary for their studies. View detailed information on our available crosslinkers by clicking on the product name.

Items 171 to 180 of 343 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

4-Hydroxy-3-methoxybenzyl alcohol

498-00-0sc-254678
100 g
$109.00
(0)

4-Hydroxy-3-methoxybenzyl alcohol acts as an effective crosslinker, exhibiting strong hydrogen bonding capabilities that enhance network formation in polymer matrices. Its hydroxyl and methoxy groups facilitate unique interactions with various functional groups, promoting a diverse range of crosslinking pathways. The compound's reactivity is influenced by steric effects, allowing for controlled reaction kinetics and the development of materials with improved elasticity and durability.

4-Bromobutyryl chloride

927-58-2sc-238794
5 g
$28.00
(0)

4-Bromobutyryl chloride serves as a potent crosslinker, characterized by its reactive acyl chloride functionality. This compound engages in acylation reactions, facilitating the formation of covalent bonds with nucleophilic sites in polymers. Its bromine substituent enhances electrophilicity, promoting rapid reaction kinetics. The resulting crosslinked structures exhibit enhanced mechanical properties and stability, making them suitable for diverse applications in material science.

Tetrahydropyranylethyleneglycol

2162-31-4sc-213021
1 g
$320.00
(0)

Tetrahydropyranylethyleneglycol serves as a versatile crosslinker, characterized by its ability to form robust ether linkages through its hydroxyl groups. This compound exhibits unique reactivity with isocyanates and epoxides, facilitating rapid crosslinking under mild conditions. Its flexible molecular structure enhances compatibility with various substrates, promoting effective network formation. Additionally, the presence of the tetrahydropyranyl group provides protection against premature reactions, ensuring stability during processing.

Tetrahydropyranyldiethyleneglycol

2163-11-3sc-220221
250 mg
$330.00
(0)

Tetrahydropyranyldiethyleneglycol functions as a versatile crosslinker, distinguished by its unique ability to engage in dynamic hydrogen bonding and hydrophobic interactions. This compound facilitates the formation of intricate polymer networks through its multi-functional structure, allowing for tunable crosslinking density. Its compatibility with diverse substrates enhances the mechanical properties of materials, while its moderate reactivity ensures controlled polymerization pathways, leading to tailored material characteristics.

4-(Hydroxymethyl)benzoic acid

3006-96-0sc-214213
sc-214213A
1 g
10 g
$58.00
$417.00
(0)

4-(Hydroxymethyl)benzoic acid serves as a versatile crosslinker, exhibiting strong hydrogen bonding capabilities due to its hydroxymethyl group. This functionality facilitates the formation of stable networks in polymer matrices, enhancing mechanical properties. Its aromatic structure contributes to π-π stacking interactions, promoting effective crosslinking pathways. Additionally, the compound's reactivity with various functional groups allows for tailored modifications, optimizing material performance in diverse applications.

N-Trifluoroacetylglycine, N-Succinimidyl Ester

3397-30-6sc-219257
25 mg
$360.00
(0)

N-Trifluoroacetylglycine, N-Succinimidyl Ester serves as an effective crosslinker, notable for its trifluoroacetyl moiety that enhances electrophilicity, promoting rapid acylation reactions. This compound's unique reactivity with amines allows for the formation of stable linkages, while its ester functionality provides a pathway for hydrolysis under specific conditions. The presence of the succinimidyl group facilitates selective targeting, enabling tailored crosslinking strategies in complex biomolecular systems.

3,4-Dihydro-2H-pyran-2-methanol

3749-36-8sc-254531
5 ml
$213.00
(0)

3,4-Dihydro-2H-pyran-2-methanol serves as a versatile crosslinker, characterized by its cyclic ether structure that allows for unique ring-opening reactions. This compound can engage in both covalent and non-covalent interactions, enhancing the mechanical properties of polymer matrices. Its ability to form stable networks through dynamic bonding pathways contributes to improved thermal stability and flexibility, making it a valuable component in advanced material formulations.

6-Bromo-1-hexanol

4286-55-9sc-239090
sc-239090A
sc-239090B
sc-239090C
5 g
100 g
500 g
1 kg
$92.00
$214.00
$656.00
$1082.00
(0)

6-Bromo-1-hexanol serves as a versatile crosslinker, characterized by its ability to form robust covalent bonds through nucleophilic substitution reactions. The bromine atom enhances reactivity, enabling efficient crosslinking in polymer matrices. Its linear structure promotes flexibility, allowing for tailored network formation. Additionally, the presence of the hydroxyl group contributes to hydrogen bonding, further stabilizing the crosslinked structure and influencing mechanical properties.

1,8-Octadiyl Bismethanethiosulfonate

4356-71-2sc-208815
25 mg
$330.00
(0)

1,8-Octadiyl Bismethanethiosulfonate functions as an effective crosslinker, exhibiting unique reactivity through its thiol groups that facilitate robust covalent bonding. Its long hydrocarbon chain enhances flexibility and compatibility with various polymer matrices, promoting uniform crosslinking. The compound's ability to form stable thiosulfinate linkages contributes to improved mechanical properties and thermal stability in composite materials, making it a key player in material science applications.

1,6-Bis-maleimidohexane

4856-87-5sc-357486
100 mg
$274.00
(0)

1,6-Bis-maleimidohexane serves as an effective crosslinker due to its ability to form stable covalent bonds through thiol-ene click chemistry. The presence of multiple maleimide groups allows for versatile crosslinking pathways, enhancing network formation in polymer matrices. Its reactivity with thiol groups is rapid, promoting efficient curing processes. Additionally, the compound exhibits excellent thermal stability, contributing to the durability of the resulting materials.