Molecular structure of Bis(3,5-dibromosalicyl) succinate, CAS Number: 71337-52-5
Bis(3,5-dibromosalicyl) succinate (CAS 71337-52-5)
Application:
Bis(3,5-dibromosalicyl) succinate is an acetylating agent of intracellular hemoglobin
CAS Number:
71337-52-5
Molecular Weight:
673.88
Molecular Formula:
C18H10O8Br4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Bis(3,5-dibromosalicyl) succinate is a potent acylating agent of intracellular hemoglobin. Cross-links beta chains of hemoglobin.
Bis(3,5-dibromosalicyl) succinate (CAS 71337-52-5) References
- Molecular necklaces. Cross-linking hemoglobin with reagents containing covalently attached ligands. | Crapatureanu, S., et al. 1999. Bioconjug Chem. 10: 1058-67. PMID: 10563776
- Allosteric inhibition of [(125I)] ET-1 binding to ET(A) receptors by aldoxime and hydroxamic acid derivatives. | Ahmed, M., et al. 2008. Med Chem. 4: 298-308. PMID: 18673140
- Polymerization of modified diaspirin cross-linked hemoglobin (DCLHb) with 1,6-bismaleimic-hexane. | Qi, D., et al. 2016. Artif Cells Nanomed Biotechnol. 44: 1069-74. PMID: 26838092
- Pharmacological actions of diaspirins, potential antisickling agents: analgesic and anti-inflammatory effects. | Thompson, EB. and Klotz, IM. 1985. Res Commun Chem Pathol Pharmacol. 48: 381-8. PMID: 4023420
- Diaspirins that cross-link beta chains of hemoglobin: bis(3,5-dibromosalicyl) succinate and bis(3,5-dibromosalicyl) fumarate. | Walder, JA., et al. 1979. Biochemistry. 18: 4265-70. PMID: 486423
- Alternative diaspirins for modification of hemoglobin and sickle hemoglobin. | Delaney, EJ., et al. 1984. Arch Biochem Biophys. 228: 627-38. PMID: 6696450
- Structural specificities in acylation of hemoglobin and sickle hemoglobin by diaspirins. | Wood, LE., et al. 1981. J Biol Chem. 256: 7046-52. PMID: 7240262
- Modification of hemoglobin with analogs of aspirin. | Zaugg, RH., et al. 1980. J Biol Chem. 255: 2816-21. PMID: 7358711
- Development of antisickling compounds that chemically modify hemoglobin S specifically within the 2,3-diphosphoglycerate binding site. | Walder, JA., et al. 1980. J Mol Biol. 141: 195-216. PMID: 7441751
- Thermal stabilities of hemoglobins crosslinked with different length reagents. | Huang, H. and Olsen, KW. 1994. Artif Cells Blood Substit Immobil Biotechnol. 22: 719-24. PMID: 7994393
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Bis(3,5-dibromosalicyl) succinate, 100 mg | sc-205228 | 100 mg | $35.00 | |||
Bis(3,5-dibromosalicyl) succinate, 500 mg | sc-205228A | 500 mg | $121.00 | |||
Bis(3,5-dibromosalicyl) succinate, 1 g | sc-205228B | 1 g | $242.00 | |||
Bis(3,5-dibromosalicyl) succinate, 5 g | sc-205228C | 5 g | $750.00 | |||
Bis(3,5-dibromosalicyl) succinate, 50 g | sc-205228D | 50 g | $6005.00 | |||
Bis(3,5-dibromosalicyl) succinate, 100 g | sc-205228E | 100 g | $10000.00 |