GCN5 Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Butyrolactone 3 | 778649-18-6 | sc-358657 sc-358657A sc-358657B | 5 mg 50 mg 100 mg | $219.00 $1467.00 $2819.00 | 3 | |
Butyrolactone 3 is a selective GCN5 inhibitor that likely impacts the acetyltransferase activity of GCN5. By binding to its active site, MB-3 interferes with the enzyme's ability to acetylate histone substrates. This inhibition can lead to altered chromatin structure and transcriptional regulation, influencing cellular processes related to gene expression and epigenetic modifications. | ||||||
L-Arginine | 74-79-3 | sc-391657B sc-391657 sc-391657A sc-391657C sc-391657D | 5 g 25 g 100 g 500 g 1 kg | $20.00 $31.00 $61.00 $219.00 $352.00 | 2 | |
L-Arginine, an amino acid, has been suggested to inhibit GCN5's acetyltransferase activity. Its mechanism might involve competing with acetyl-CoA, a co-substrate, for binding to GCN5's active site. This competition could reduce histone acetylation and influence gene expression patterns associated with chromatin remodeling and transcriptional regulation. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin, a natural polyphenol, might influence GCN5's activity through various mechanisms, including direct interaction with the enzyme's active site or indirect modulation of its expression. By impacting GCN5's function, curcumin could affect histone acetylation patterns and contribute to its anti-inflammatory and anticancer effects. | ||||||
Anacardic Acid | 16611-84-0 | sc-202463 sc-202463A | 5 mg 25 mg | $102.00 $204.00 | 13 | |
Anacardic acid, found in cashew nut shells, is thought to inhibit GCN5 through competitive binding with acetyl-CoA. This competition could hinder GCN5's acetyltransferase activity, leading to reduced histone acetylation levels and alterations in chromatin structure and gene expression associated with transcriptional regulation. | ||||||
Plumbagin | 481-42-5 | sc-253283 sc-253283A | 100 mg 250 mg | $52.00 $62.00 | 6 | |
Plumbagin is a natural compound that might influence GCN5's activity indirectly through its effects on cellular signaling pathways and gene expression. While specific mechanisms are not well-established, its impact on GCN5 could contribute to its reported anticancer properties and modulation of transcriptional processes. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin, a flavonoid, has been investigated for its potential to inhibit GCN5. Its exact mechanism might involve interference with GCN5's acetyltransferase activity, leading to modifications in histone acetylation and gene expression patterns associated with transcriptional regulation and epigenetic control. | ||||||
Garcinol | 78824-30-3 | sc-200891 sc-200891A | 10 mg 50 mg | $124.00 $502.00 | 13 | |
Garcinol is a polyisoprenylated benzophenone compound that likely inhibits GCN5's acetyltransferase activity. It binds to the enzyme's active site, blocking its interaction with histone substrates and interfering with the acetylation of histones. This inhibition can impact gene expression, chromatin remodeling, and various cellular processes governed by GCN5-mediated acetylation. | ||||||
6-Azauridine | 54-25-1 | sc-221082B sc-221082 sc-221082C sc-221082A | 500 mg 1 g 2 g 5 g | $97.00 $159.00 $295.00 $679.00 | ||
6-Azauridine is a pyrimidine analog that could potentially impact GCN5's activity, although specific information is limited. Its mechanism might involve interference with GCN5's acetyltransferase function, leading to altered histone acetylation patterns and changes in gene expression and cellular processes influenced by chromatin remodeling. | ||||||