Date published: 2026-2-11

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GCN2 Antibodies

Santa Cruz Biotechnology delivers a wide array of GCN2 monoclonal antibodies for research focused on understanding GCN2's role in cellular stress responses. GCN2 monoclonal antibodies are suitable for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). GCN2, or General Control Nonderepressible 2, is a serine/threonine kinase that plays a central role in the cellular response to amino acid deprivation and other stressors. Through phosphorylation of eIF2α, GCN2 modulates protein synthesis and helps maintain cellular homeostasis under stress conditions. Research into GCN2 function continues to reveal important mechanisms of stress adaptation and potential connections to various diseases, including cancer and neurodegeneration. Investigating GCN2 pathways provides researchers with deeper understanding of cellular stress responses and their impact on disease progression. GCN2 research has highlighted significant roles in amino acid sensing and cellular adaptation mechanisms. Exploring GCN2 signaling networks helps illuminate fundamental aspects of cellular homeostasis. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to advance scientific understanding of stress response pathways and their implications in human health and disease.

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GCN2 Antibodies

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GCN2 Antibody (F-7)

sc-374609mouse IgG1 κ1350-1649 (h)WB, IP, IF, IHC(P), ELISAh
15
(7)

GCN2 CRISPR Knockout, HDR and Double Nickase Plasmids

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GCN2 CRISPR/Cas9 KO Plasmid (h)

sc-402313hGene KnockoutGFP
1
(0)

GCN2 HDR Plasmid (h)

sc-402313-HDRhHomology Directed RepairPuromycin
1
(0)

GCN2 Double Nickase Plasmid (h)

sc-402313-NIChGene KnockoutPuromycin
1
(0)

GCN2 Double Nickase Plasmid (h2)

sc-402313-NIC-2hGene KnockoutPuromycin
1
(0)

GCN2 CRISPR/Cas9 KO Plasmid (m)

sc-424196mGene KnockoutGFP0
(0)

GCN2 HDR Plasmid (m)

sc-424196-HDRmHomology Directed RepairPuromycin0
(0)

GCN2 Double Nickase Plasmid (m)

sc-424196-NICmGene KnockoutPuromycin0
(0)

GCN2 Double Nickase Plasmid (m2)

sc-424196-NIC-2mGene KnockoutPuromycin0
(0)

GCN2 CRISPR Activation Products

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GCN2 CRISPR Activation Plasmid (h)

sc-402313-ACThGene ActivationPuro, Blast, Hygro
1
(0)

GCN2 CRISPR Activation Plasmid (m)

sc-424196-ACTmGene ActivationPuro, Blast, Hygro0
(0)

GCN2 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

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GCN2 siRNA (h)

sc-45644hGene SilencingN/A
14
(0)

GCN2 shRNA Plasmid (h)

sc-45644-SHhGene SilencingPuromycin
14
(0)

GCN2 shRNA (h) Lentiviral Particles

sc-45644-VhGene SilencingPuromycin
14
(0)

GCN2 siRNA (m)

sc-45645mGene SilencingN/A
3
(0)

GCN2 shRNA Plasmid (m)

sc-45645-SHmGene SilencingPuromycin
3
(0)

GCN2 shRNA (m) Lentiviral Particles

sc-45645-VmGene SilencingPuromycin
3
(0)