Date published: 2026-7-3

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GCN2 Antibodies

Santa Cruz Biotechnology delivers a wide array of GCN2 monoclonal antibodies for research focused on understanding GCN2's role in cellular stress responses. GCN2 monoclonal antibodies are suitable for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). GCN2, or General Control Nonderepressible 2, is a serine/threonine kinase that plays a central role in the cellular response to amino acid deprivation and other stressors. Through phosphorylation of eIF2α, GCN2 modulates protein synthesis and helps maintain cellular homeostasis under stress conditions. Research into GCN2 function continues to reveal important mechanisms of stress adaptation and potential connections to various diseases, including cancer and neurodegeneration. Investigating GCN2 pathways provides researchers with deeper understanding of cellular stress responses and their impact on disease progression. GCN2 research has highlighted significant roles in amino acid sensing and cellular adaptation mechanisms. Exploring GCN2 signaling networks helps illuminate fundamental aspects of cellular homeostasis. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to advance scientific understanding of stress response pathways and their implications in human health and disease.

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GCN2 Antibodies

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GCN2 Antibody (F-7)

sc-374609mouse IgG1 κ1350-1649 (h)WB, IP, IF, IHC(P), ELISAh
15
(7)

GCN2 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

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GCN2 siRNA (h)

sc-45644hGene SilencingN/A
14
(0)

GCN2 shRNA Plasmid (h)

sc-45644-SHhGene SilencingPuromycin
14
(0)

GCN2 shRNA (h) Lentiviral Particles

sc-45644-VhGene SilencingPuromycin
14
(0)

GCN2 siRNA (m)

sc-45645mGene SilencingN/A
3
(0)

GCN2 shRNA Plasmid (m)

sc-45645-SHmGene SilencingPuromycin
3
(0)

GCN2 shRNA (m) Lentiviral Particles

sc-45645-VmGene SilencingPuromycin
3
(0)

GCN2 CRISPR Knockout (KO) and HDR Plasmids

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GCN2 CRISPR/Cas9 KO Plasmid (h)

sc-402313Gene Knockouth0
(0)

GCN2 HDR Plasmid (h)

sc-402313-HDRHomology Directed Repairh0
(0)

GCN2 CRISPR/Cas9 KO Plasmid (m)

sc-424196Gene Knockoutm0
(0)

GCN2 HDR Plasmid (m)

sc-424196-HDRHomology Directed Repairm0
(0)

GCN2 CRISPR Double Nickase Plasmids

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GCN2 Double Nickase Plasmid (h)

sc-402313-NICGene Knockouth0
(0)

GCN2 Double Nickase Plasmid (h2)

sc-402313-NIC-2Gene Knockouth0
(0)

GCN2 Double Nickase Plasmid (m)

sc-424196-NICGene Knockoutm0
(0)

GCN2 Double Nickase Plasmid (m2)

sc-424196-NIC-2Gene Knockoutm0
(0)

GCN2 CRISPR Activation Plasmids and Lentiviral Particles

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GCN2 CRISPR Activation Plasmid (h)

sc-402313-ACTGene Activationh0
(0)

GCN2 CRISPR Activation Plasmid (m)

sc-424196-ACTGene Activationm0
(0)