Date published: 2025-12-12

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GATSL3 Activators

GATSL3 Activators belong to a specialized class of chemical compounds that primarily target the activation of the GATSL3 protein. To understand this class better, we must first delve into the components it involves. GATSL3, or Glutaminase C Activating Small Molecule Ligand 3, is a protein that plays a crucial role in various biochemical pathways within the cell. It is involved in the regulation of glutamine metabolism, an essential process for the growth and proliferation of cells. In essence, GATSL3 is part of the intricate network that regulates cellular energy metabolism and amino acid utilization, making it a significant player in maintaining cellular homeostasis.

GATSL3 Activators are designed with the specific purpose of enhancing the activity of GATSL3. These molecules may function by directly binding to the GATSL3 protein, promoting its stability, or modulating its enzymatic activity. By doing so, they can influence the rate of glutamine metabolism and impact various downstream cellular processes. Given the pivotal role of glutamine in cell growth and proliferation, GATSL3 Activators hold great promise in the context of research and potential applications in cellular biology. Researchers are keenly interested in these compounds because they provide a valuable tool to study the intricate mechanisms of cellular metabolism, opening up possibilities for deeper insights into diseases and cellular function. Consequently, GATSL3 Activators represent an important category of molecules with the potential to shed light on fundamental biological processes and may find applications in various fields of life science research.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$65.00
$319.00
$575.00
$998.00
28
(1)

Retinoic acid is a derivative of vitamin A that activates GATSL3 by binding to retinoic acid receptors (RARs).

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$76.00
$150.00
$725.00
$1385.00
$2050.00
73
(3)

Forskolin activates GATSL3 indirectly by increasing intracellular cAMP levels, leading to PKA activation.

PMA

16561-29-8sc-3576
sc-3576A
sc-3576B
sc-3576C
sc-3576D
1 mg
5 mg
10 mg
25 mg
100 mg
$40.00
$129.00
$210.00
$490.00
$929.00
119
(6)

PMA activates GATSL3 by stimulating protein kinase C (PKC), which can modulate GATSL3 through phosphorylation.

8-Bromo-cAMP

76939-46-3sc-201564
sc-201564A
10 mg
50 mg
$97.00
$224.00
30
(1)

8-Bromo-cAMP activates GATSL3 by increasing intracellular cAMP levels and influencing downstream signaling.

Sodium Butyrate

156-54-7sc-202341
sc-202341B
sc-202341A
sc-202341C
250 mg
5 g
25 g
500 g
$30.00
$46.00
$82.00
$218.00
19
(3)

Sodium butyrate may activate GATSL3 indirectly by affecting histone acetylation and gene expression.