GAGE7B Inhibitors
GAGE7B inhibitors constitute a specialized chemical class designed to selectively modulate the activity of the GAGE7B protein. GAGE7B belongs to the GAGE family of proteins, recognized for their association with cancer and the immune system. Specifically, GAGE7B is implicated in various cellular processes, including cell cycle regulation and modulation of immune responses. Inhibitors targeting GAGE7B operate by disrupting its normal functions within these pathways, thereby influencing the intricate balance of cellular activities that involve this protein.
The precise mechanism of action for GAGE7B inhibitors involves interfering with the molecular interactions and signaling cascades in which GAGE7B is involved. By perturbing these pathways, these inhibitors can potentially influence cellular processes regulated by GAGE7B, providing researchers with valuable tools to explore the intricate molecular networks associated with cancer and immune modulation. Understanding the role of GAGE7B and the impact of its inhibition contributes to the broader knowledge of cellular biology and may pave the way for further research into the complex interplay between cancer and the immune system. GAGE7B inhibitors serve as indispensable assets in deciphering the molecular intricacies of these pathways and expanding our comprehension of the biological factors influencing cellular behavior.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Disulfiram | 97-77-8 | sc-205654 sc-205654A | 50 g 100 g | $53.00 $89.00 | 7 | |
Disulfiram can modulate DNA methylation and histone acetylation, potentially influencing the expression of genes like GAGE7B. | ||||||
Hydralazine-15N4 Hydrochloride | 304-20-1 (unlabeled) | sc-490605 | 1 mg | $480.00 | ||
Hydralazine may induce DNA demethylation and reactivate the expression of tumor suppressor genes, which could indirectly affect GAGE7B expression. | ||||||
Caffeic acid phenethyl ester | 104594-70-9 | sc-200800 sc-200800A sc-200800B | 20 mg 100 mg 1 g | $71.00 $296.00 $612.00 | 19 | |
CAPE can inhibit DNA methyltransferases, possibly leading to hypomethylation and alteration of gene expression. | ||||||
Sinefungin | 58944-73-3 | sc-203263 sc-203263B sc-203263C sc-203263A | 1 mg 100 mg 1 g 10 mg | $271.00 $5202.00 $40368.00 $704.00 | 4 | |
Sinefungin is an adenosylmethionine decarboxylase inhibitor, which could lead to a reduction in methylation and changes in gene expression. | ||||||
Scriptaid | 287383-59-9 | sc-202807 sc-202807A | 1 mg 5 mg | $64.00 $183.00 | 11 | |
Scriptaid is an HDAC inhibitor that can alter chromatin structure, potentially affecting the expression of genes such as GAGE7B. | ||||||
Mocetinostat | 726169-73-9 | sc-364539 sc-364539B sc-364539A | 5 mg 10 mg 50 mg | $214.00 $247.00 $1463.00 | 2 | |
An HDAC inhibitor that may change chromatin dynamics and thus influence gene expression patterns, including those of cancer/testis antigens. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin has been shown to have DNA demethylating activity, which may influence the expression of various genes. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG, the main catechin in green tea, has been reported to affect DNA methylation and histone modification processes. | ||||||
Zebularine | 3690-10-6 | sc-203315 sc-203315A sc-203315B | 10 mg 25 mg 100 mg | $129.00 $284.00 $1004.00 | 3 | |
Zebularine is a DNA methyltransferase inhibitor and cytidine analog that can be incorporated into DNA, leading to demethylation. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $218.00 $322.00 $426.00 | 7 | |
A DNA methyltransferase inhibitor that can cause hypomethylation and potentially affect gene expression, possibly including GAGE7B. | ||||||