Fyn Inhibitors
Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
SU6656 | 330161-87-0 | sc-203286 sc-203286A | 1 mg 5 mg | $56.00 $130.00 | 27 | |
SU6656 is a selective Src family kinase inhibitor, and it may decrease Fyn kinase activity and associated pathways. | ||||||
PP 2 | 172889-27-9 | sc-202769 sc-202769A | 1 mg 5 mg | $92.00 $223.00 | 30 | |
PP2 is a selective inhibitor of Src-family kinases, including Fyn, blocking its kinase activity and potentially reducing its expression. | ||||||
1-Naphthyl PP1 | 221243-82-9 | sc-203765 sc-203765A | 10 mg 50 mg | $230.00 $964.00 | 3 | |
1-Naphthyl PP1 acts as a selective inhibitor of Fyn, showcasing unique molecular interactions that disrupt its kinase activity. The compound's naphthyl moiety facilitates hydrophobic interactions with the enzyme, enhancing binding specificity. Kinetic analyses indicate a competitive inhibition mechanism, where the presence of 1-Naphthyl PP1 alters the phosphorylation dynamics of target substrates. Its distinct structural features contribute to a nuanced modulation of signaling pathways, influencing cellular responses. | ||||||
Dasatinib | 302962-49-8 | sc-358114 sc-358114A | 25 mg 1 g | $47.00 $145.00 | 51 | |
Dasatinib is a multi-target kinase inhibitor that can inhibit Fyn kinase activity. This could lead to reduced Fyn signaling and downstream effects. | ||||||
PP 1 | 172889-26-8 | sc-203212 sc-203212A | 1 mg 5 mg | $84.00 $142.00 | 6 | |
PP 1 is a potent inhibitor of Fyn, characterized by its ability to form stable complexes with the kinase. The compound's unique structural elements promote specific hydrogen bonding and van der Waals interactions, which enhance its affinity for the active site. Kinetic studies reveal that PP 1 exhibits non-competitive inhibition, effectively altering the enzyme's conformational dynamics. This modulation leads to significant changes in downstream signaling cascades, impacting cellular behavior. | ||||||
A 419259 trihydrochloride | 1435934-25-0 | sc-361094 | 5 mg | $209.00 | 6 | |
A-419259 is an Src-family kinase inhibitor, and it might inhibit Fyn activity, affecting its downstream pathways. | ||||||
Lck Inhibitor Inhibitor | 213743-31-8 | sc-204052 | 1 mg | $355.00 | 5 | |
Lck Inhibitor is a selective modulator of Fyn, distinguished by its capacity to disrupt ATP binding through unique electrostatic interactions. Its design facilitates specific hydrophobic contacts that stabilize the inhibitor-kinase complex, resulting in altered reaction kinetics. This compound exhibits allosteric inhibition, influencing the enzyme's structural conformation and subsequently affecting the phosphorylation state of target substrates, thereby reshaping cellular signaling networks. | ||||||
Saracatinib | 379231-04-6 | sc-364607 sc-364607A | 10 mg 200 mg | $113.00 $1035.00 | 7 | |
Saracatinib selectively inhibits Src-family kinases, including Fyn, potentially reducing its activity and signaling. | ||||||
PD 173955 | 260415-63-2 | sc-507378 | 10 mg | $320.00 | ||
PD173955 inhibits Src-family kinases and can potentially reduce Fyn activity and its downstream effects. | ||||||
Herbimycin A | 70563-58-5 | sc-3516 sc-3516A | 100 µg 1 mg | $272.00 $1502.00 | 13 | |
Herbimycin A is an antibiotic that inhibits Src-family kinases. It could decrease Fyn kinase activity and its associated signaling. | ||||||