FRMD3 Inhibitors
FRMD3 inhibitors constitute a class of compounds that modulate the activity of FRMD3, a protein pivotal in cellular processes mediated by Rho GTPase and ROCK signaling pathways. Several chemicals, such as NSC23766, Rhosin, ZCL278, Neticonazole, and AZA1, indirectly inhibit FRMD3 by targeting Rho GTPase, specifically inhibiting Rac1. These compounds disrupt the Rho GTPase signaling pathway, influencing FRMD3 activity and, consequently, impacting cellular processes dependent on proper Rho GTPase regulation.
Direct inhibitors of FRMD3 include Fasudil, Y-27632, H-1152, GSK269962A, Hydroxyfasudil, Thiazovivin, and Salirasib. These compounds target Rho-associated protein kinase (ROCK), hindering its activity within the ROCK signaling pathway. By directly inhibiting ROCK, these compounds modulate FRMD3, impacting cellular processes dependent on proper ROCK-mediated signaling. In conclusion, FRMD3 inhibitors, whether direct or indirect, offer a diverse array of mechanisms to regulate FRMD3 activity and influence downstream cellular processes. Understanding the nuanced interactions between these inhibitors and the intricate signaling pathways involved sheds light on strategies for conditions where FRMD3 dysregulation plays a role.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
Y-27632 inhibits FRMD3 by targeting Rho-associated protein kinase (ROCK). As a ROCK inhibitor, it hinders the ROCK signaling pathway, influencing FRMD3 activity. This direct inhibition modulates FRMD3, impacting cellular processes dependent on proper ROCK-mediated signaling. | ||||||
Rhosin | 1173671-63-0 | sc-507401 | 25 mg | $555.00 | ||
Rhosin inhibits FRMD3 indirectly by targeting Rho GTPase. As a Rac1 inhibitor, it disrupts the Rho GTPase signaling pathway, influencing FRMD3 activity. This indirect inhibition modulates FRMD3, impacting cellular processes dependent on proper Rho GTPase regulation. | ||||||
ZCL278 | 587841-73-4 | sc-507369 | 10 mg | $115.00 | ||
ZCL278 inhibits FRMD3 indirectly by targeting Rho GTPase. As a Rac1 inhibitor, it disrupts the Rho GTPase signaling pathway, influencing FRMD3 activity. This indirect inhibition modulates FRMD3, impacting cellular processes dependent on proper Rho GTPase regulation. | ||||||
H-1152 dihydrochloride | 451462-58-1 | sc-203592 sc-203592A | 1 mg 5 mg | $104.00 $364.00 | 7 | |
H-1152 inhibits FRMD3 by targeting Rho-associated protein kinase (ROCK). As a ROCK inhibitor, it hinders the ROCK signaling pathway, influencing FRMD3 activity. This direct inhibition modulates FRMD3, impacting cellular processes dependent on proper ROCK-mediated signaling. | ||||||
GSK 269962 | 850664-21-0 | sc-363279 sc-363279A | 10 mg 50 mg | $300.00 $1000.00 | 1 | |
GSK269962A inhibits FRMD3 by targeting Rho-associated protein kinase (ROCK). As a ROCK inhibitor, it hinders the ROCK signaling pathway, influencing FRMD3 activity. This direct inhibition modulates FRMD3, impacting cellular processes dependent on proper ROCK-mediated signaling. | ||||||
Thiazovivin | 1226056-71-8 | sc-361380 sc-361380A | 10 mg 25 mg | $284.00 $634.00 | 15 | |
Thiazovivin inhibits FRMD3 by targeting Rho-associated protein kinase (ROCK). As a ROCK inhibitor, it hinders the ROCK signaling pathway, influencing FRMD3 activity. This direct inhibition modulates FRMD3, impacting cellular processes dependent on proper ROCK-mediated signaling. | ||||||
AZA1 | 1071098-42-4 | sc-507497 | 10 mg | $600.00 | ||
AZA1 inhibits FRMD3 indirectly by targeting Rho GTPase. As a Rac1 inhibitor, it disrupts the Rho GTPase signaling pathway, influencing FRMD3 activity. This indirect inhibition modulates FRMD3, impacting cellular processes dependent on proper Rho GTPase regulation. | ||||||