Formin Like (FMNL1, FMNL2) Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $165.00 $486.00 | 64 | |
It binds to the barbed ends of actin filaments, preventing further polymerization and leading to filament depolymerization. | ||||||
Latrunculin A, Latrunculia magnifica | 76343-93-6 | sc-202691 sc-202691B | 100 µg 500 µg | $265.00 $815.00 | 36 | |
This compound binds to actin monomers, sequestering them and preventing their polymerization into filaments. | ||||||
Phalloidin | 17466-45-4 | sc-202763 | 1 mg | $234.00 | 33 | |
Although not a small molecule but a toxin, phalloidin binds tightly to F-actin, stabilizing it and preventing its depolymerization. It's often used in research for staining actin filaments in cells. | ||||||
Swinholide A, Theonella swinhoei | 95927-67-6 | sc-205914 | 10 µg | $135.00 | ||
This compound severs actin filaments and caps their newly formed ends, thereby disrupting the actin cytoskeleton. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
A ROCK (Rho-associated protein kinase) inhibitor, indirectly affects actin dynamics by altering the phosphorylation state of myosin light chains and other substrates of ROCK involved in actin filament organization. | ||||||
(±)-Blebbistatin | 674289-55-5 | sc-203532B sc-203532 sc-203532A sc-203532C sc-203532D | 5 mg 10 mg 25 mg 50 mg 100 mg | $183.00 $313.00 $464.00 $942.00 $1723.00 | 7 | |
An inhibitor of myosin II ATPase activity, blebbistatin disrupts myosin II-mediated contractility and thus indirectly affects actin filament organization. | ||||||
SMIFH2 | 340316-62-3 | sc-507273 | 5 mg | $140.00 | ||
This molecule inhibits formin-mediated actin nucleation and elongation, affecting the actin cytoskeleton indirectly. | ||||||
CK 666 | 442633-00-3 | sc-361151 sc-361151A | 10 mg 50 mg | $321.00 $1040.00 | 5 | |
An inhibitor of the Arp2/3 complex, it disrupts the branching of actin filaments. | ||||||