Date published: 2026-5-16

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FKBPL Inhibitors

FKBPL inhibitors represent a class of chemical compounds that have garnered substantial attention in the realm of molecular research due to their unique ability to modulate the function of FKBPL, which stands for FK506-binding protein-like. FKBPL is a protein found in cells that plays an essential role in various cellular processes. FKBPL inhibitors are designed to interact with this protein, often by binding to its active sites, in order to influence its function. By specifically targeting FKBPL, these inhibitors provide researchers with a powerful tool for studying cellular pathways and the intricate regulatory mechanisms associated with this protein. FKBPL inhibitors exhibit a diverse range of chemical structures, each tailored to interact with FKBPL in a specific manner. This diversity allows scientists to conduct experiments and investigations into the functions of FKBPL in a variety of biological contexts. Such inhibitors can either suppress or enhance the activity of FKBPL, thus contributing to a better understanding of how this protein participates in cell signaling, protein-protein interactions, and other cellular processes. The insights gained from the use of FKBPL inhibitors offer valuable contributions to basic research and expand our knowledge of the molecular intricacies that govern cellular function.

Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Geldanamycin

30562-34-6sc-200617B
sc-200617C
sc-200617
sc-200617A
100 µg
500 µg
1 mg
5 mg
$39.00
$59.00
$104.00
$206.00
8
(1)

Binds to Hsp90, inhibiting chaperone function, leading to misfolding and degradation of FKBPL.

Radicicol

12772-57-5sc-200620
sc-200620A
1 mg
5 mg
$92.00
$333.00
13
(1)

Hsp90 inhibitor that disrupts protein folding, destabilizing FKBPL and other client proteins.

17-AAG

75747-14-7sc-200641
sc-200641A
1 mg
5 mg
$67.00
$156.00
16
(2)

Destabilizes Hsp90-client protein complexes, leading to FKBPL degradation and loss of function.

FK-506

104987-11-3sc-24649
sc-24649A
5 mg
10 mg
$78.00
$151.00
9
(1)

Binds to FKBP12, inhibiting its isomerase activity, indirectly affecting FKBPL function.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$63.00
$158.00
$326.00
233
(4)

Forms a complex with FKBP12, inhibiting mTOR, impacting FKBPL regulation and cellular processes.

Cyclosporin A

59865-13-3sc-3503
sc-3503-CW
sc-3503A
sc-3503B
sc-3503C
sc-3503D
100 mg
100 mg
500 mg
10 g
25 g
100 g
$63.00
$92.00
$250.00
$485.00
$1035.00
$2141.00
69
(5)

Binds to cyclophilin, disrupting its activity and potentially affecting FKBPL through shared pathways.

NVP-AUY922

747412-49-3sc-364551
sc-364551A
sc-364551B
sc-364551C
sc-364551D
sc-364551E
5 mg
25 mg
100 mg
250 mg
1 g
5 g
$150.00
$263.00
$726.00
$1400.00
$2900.00
$11000.00
3
(1)

Hsp90 inhibitor, disrupting Hsp90-client protein interactions, leading to FKBPL degradation.

Heat Shock Protein Inhibitor I

218924-25-5sc-221709
5 mg
$97.00
5
(1)

Targets HSF1, affecting heat shock protein regulation and indirectly influencing FKBPL under stress conditions.

Cisplatin

15663-27-1sc-200896
sc-200896A
100 mg
500 mg
$138.00
$380.00
101
(4)

Induces DNA damage and cellular stress responses, indirectly affecting FKBPL expression and function.

17-DMAG

467214-20-6sc-202005
1 mg
$205.00
8
(1)

Hsp90 inhibitor, disrupting Hsp90-client protein complexes, leading to FKBPL degradation and loss of function.