FEM1A Activators
The chemical class termed FEM1A Activators encompasses a broad spectrum of compounds that, rather than directly stimulating FEM1A, exert their influence on the cellular pathways that can lead to the upregulation or increased activity of FEM1A. These compounds interact with a variety of signaling molecules and pathways, such as Wnt, cAMP, PI3K/AKT, MAPKs, and others, to create a cellular context in which the activity of FEM1A is indirectly enhanced.
Through a diversity of mechanisms, such as the inhibition of kinases, alteration of gene expression via epigenetic modifications, or modulation of the cellular redox state, these activators can influence the signaling cascades that converge on the regulation of apoptosis and cell survival. For instance, lithium chloride's inhibition of GSK-3β stabilizes β-catenin, affecting pathways involving FEM1A. Similarly, forskolin's elevation of cAMP levels can activate PKA, which may alter the phosphorylation state of various proteins in apoptotic pathways that include FEM1A. Compounds like 5-Azacytidine and trichostatin A can lead to epigenetic changes that make the genomic context more permissive for the expression of genes that may include FEM1A or its modulators
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Enhances the Wnt signaling pathway by inhibiting GSK-3β, which can lead to increased stability and transcriptional activity of β-catenin, a protein known to be involved in the same pathway as FEM1A. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Increases intracellular cAMP levels, which can activate PKA and may subsequently influence the phosphorylation state of proteins within apoptosis signaling pathways where FEM1A is a component. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
An antioxidant that can modulate signal transduction pathways, potentially influencing the expression or activity of proteins involved in cell survival and apoptosis, including FEM1A. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A DNA methyltransferase inhibitor that can lead to the demethylation and possible reactivation of genes, which may include those coding for proteins like FEM1A or its regulators. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
An HDAC inhibitor that can lead to hyperacetylation of histones, affecting gene expression, including possibly genes related to the function or regulation of FEM1A. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
A short-chain fatty acid that acts as an HDAC inhibitor and can influence gene expression, potentially affecting those genes that regulate FEM1A. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
A compound that can modulate multiple signaling pathways, including those involved in apoptosis and cell survival, potentially affecting the activity or expression of FEM1A. | ||||||