Date published: 2025-12-24

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FAM82B Activators

FAM82B, also known as RIPOR2, is a protein that is part of the RIPOR family, which includes proteins that interact with Rho family GTPases. These GTPases are key regulators of cellular processes including cytoskeletal organization, cell adhesion, and cell migration. The specific biological role of FAM82B remains to be fully elucidated, but by investigating the characteristics of the RIPOR family to which it belongs, we can infer potential functions.As a member of the RIPOR family, FAM82B is likely to be involved in the modulation of cytoskeletal dynamics. It may play a role in actin filament stabilization or reorganization, which is critical for cell shape changes, motility, and the maintenance of cell polarity. FAM82B could interact with Rho GTPases to influence signaling pathways that orchestrate the assembly or disassembly of actin structures, affecting processes such as the formation of stress fibers, lamellipodia, and filopodia.

In addition to its potential cytoskeletal functions, FAM82B may be implicated in the regulation of other cellular activities mediated by Rho GTPases, including cell cycle progression and gene transcription. It could act as a scaffold protein, bringing together multiple components of a signaling pathway to ensure efficient signal transduction.The expression pattern of FAM82B across tissues and developmental stages, as well as its subcellular localization, can provide clues about its physiological role.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

PMA

16561-29-8sc-3576
sc-3576A
sc-3576B
sc-3576C
sc-3576D
1 mg
5 mg
10 mg
25 mg
100 mg
$40.00
$129.00
$210.00
$490.00
$929.00
119
(6)

PMA activates Protein Kinase C, potentially impacting pathways involving FAM82B.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$121.00
$392.00
148
(1)

LY294002 is a PI3K inhibitor, potentially altering pathways that could indirectly modulate FAM82B.

U-0126

109511-58-2sc-222395
sc-222395A
1 mg
5 mg
$63.00
$241.00
136
(2)

U0126 inhibits MEK, which could have downstream effects on pathways involving FAM82B.

SB 203580

152121-47-6sc-3533
sc-3533A
1 mg
5 mg
$88.00
$342.00
284
(5)

SB203580 inhibits p38 MAPK, potentially affecting pathways related to FAM82B.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$62.00
$155.00
$320.00
233
(4)

Rapamycin inhibits mTOR, possibly influencing pathways associated with FAM82B.

DAPT

208255-80-5sc-201315
sc-201315A
sc-201315B
sc-201315C
5 mg
25 mg
100 mg
1 g
$99.00
$335.00
$836.00
$2099.00
47
(3)

DAPT inhibits γ-secretase, potentially affecting Notch signaling related to FAM82B.

PD 98059

167869-21-8sc-3532
sc-3532A
1 mg
5 mg
$39.00
$90.00
212
(2)

PD98059 inhibits MEK, potentially affecting pathways involving FAM82B.

SP600125

129-56-6sc-200635
sc-200635A
10 mg
50 mg
$40.00
$150.00
257
(3)

SP600125 inhibits JNK, potentially influencing signaling pathways associated with FAM82B.