FAM160A2 Inhibitors
FAM160A2 inhibitors encompass a diverse array of compounds that target various aspects of the cytoskeletal machinery, specifically those that impact the dynamics and integrity of actin filaments and microtubules. By influencing these critical components of the cellular architecture, these inhibitors exert an indirect effect on function of FAM160A2.
This protein is closely associated with the regulation and maintenance of the cytoskeleton, a network of fibers that includes actin filaments, microtubules, and intermediate filaments. These structures are responsible for various cellular functions such as maintaining shape, enabling cellular movement, and facilitating cell division.Disrupting the actin cytoskeleton with these inhibitors can lead to alterations in cell motility, adhesion, and the overall mechanics of cellular processes.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Wiskostatin | 253449-04-6 | sc-204399 sc-204399A sc-204399B sc-204399C | 1 mg 5 mg 25 mg 50 mg | $49.00 $124.00 $441.00 $828.00 | 4 | |
Wiskostatin is a specific inhibitor of the N-WASP, which is crucial for actin polymerization. FAM160A2 is associated with actin cytoskeleton dynamics; hence, wiskostatin can lead to the inhibition of FAM160A2 by destabilizing the actin cytoskeleton, disrupting the cellular processes it depends on. | ||||||
ML 141 | 71203-35-5 | sc-362768 sc-362768A | 5 mg 25 mg | $137.00 $512.00 | 7 | |
ML141 is a potent, selective inhibitor of Cdc42, a small GTPase regulating actin cytoskeleton dynamics. By inhibiting Cdc42, ML141 can prevent the downstream effects that are necessary for FAM160A2's role in cytoskeletal organization. | ||||||
CK 666 | 442633-00-3 | sc-361151 sc-361151A | 10 mg 50 mg | $321.00 $1040.00 | 5 | |
CK-666 is an Arp2/3 complex inhibitor, preventing actin nucleation and branch formation. As FAM160A2 is implicated in actin filament organization, the inhibition of actin branching by CK-666 can indirectly inhibit FAM160A2 function by preventing proper actin cytoskeleton formation. | ||||||
SMIFH2 | 340316-62-3 | sc-507273 | 5 mg | $140.00 | ||
SMIFH2 is a formin inhibitor that disrupts formin-mediated actin nucleation and elongation. FAM160A2's activity is related to the actin cytoskeleton; thus, inhibiting formin functions can lead to the inhibition of FAM160A2 by impairing actin filament dynamics. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
Y-27632 is a ROCK inhibitor that reduces actin cytoskeletal tension by inhibiting myosin light chain phosphorylation. Since FAM160A2 is involved with cytoskeletal organization, Y-27632 can indirectly inhibit FAM160A2 activity by reducing cytoskeletal tension and stability. | ||||||
Latrunculin A, Latrunculia magnifica | 76343-93-6 | sc-202691 sc-202691B | 100 µg 500 µg | $265.00 $815.00 | 36 | |
Latrunculin A binds to actin monomers and prevents their polymerization. FAM160A2's functionality is closely tied to the actin cytoskeleton, hence the disruption of actin polymerization by latrunculin A can lead to the functional inhibition of FAM160A2. | ||||||
Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $165.00 $486.00 | 64 | |
Cytochalasin D is an actin polymerization inhibitor that binds to the barbed ends of actin filaments. This binding inhibits both the elongation of actin filaments and the interactions with actin-binding proteins, which could indirectly inhibit the activity of FAM160A2. | ||||||
(S)-(−)-Blebbistatin | 856925-71-8 | sc-204253 sc-204253A sc-204253B sc-204253C | 1 mg 5 mg 10 mg 25 mg | $72.00 $265.00 $495.00 $968.00 | ||
Blebbistatin is an inhibitor of myosin II ATPase activity, leading to a decrease in myosin-driven contractility. Since FAM160A2 is associated with actin structures, the reduction in contractile forces by blebbistatin can lead to the inhibition of FAM160A2 by affecting cytoskeletal dynamics. | ||||||
Jasplakinolide | 102396-24-7 | sc-202191 sc-202191A | 50 µg 100 µg | $184.00 $305.00 | 59 | |
Jasplakinolide stabilizes actin filaments and can lead to aberrant actin polymerization. By disrupting normal actin dynamics, jasplakinolide can inhibit FAM160A2 by creating an unfavorable environment for its associated cytoskeletal processes. | ||||||
Chelerythrine | 34316-15-9 | sc-507380 | 100 mg | $540.00 | ||
Chelerythrine is a potent inhibitor of protein kinase C (PKC), which can modulate the actin cytoskeleton. The inhibition of PKC can lead to the functional inhibition of FAM160A2 by altering actin dynamics that FAM160A2 is dependent on. | ||||||