FADS7_Degs1 Activators
The first group of FADS7_Degs1 activators includes compounds that affect ceramide synthesis, either by acting as precursors for ceramide synthesis (sphingosine, sphinganine, palmitoyl-CoA, and serine) or by blocking the conversion of ceramides into other sphingolipids (C6 ceramide and PDMP). These compounds enhance the activity of FADS7_Degs1 by increasing the demand for ceramide synthesis or by increasing the availability of substrates for ceramide synthesis, respectively.
The second category of FADS7_Degs1 activators includes compounds that impact the synthesis or degradation of other sphingolipids (D609, and N,N-dimethylsphingosine). These compounds elevate the functional activity of FADS7_Degs1 by manipulating the levels of other sphingolipids. D609 and N,N-dimethylsphingosine increase the availability of substrates for ceramide synthesis, thereby indirectly enhancing FADS7_Degs1 activity.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
D609 | 83373-60-8 | sc-201403 sc-201403A | 5 mg 25 mg | $189.00 $575.00 | 7 | |
D609 is an inhibitor of phosphatidylcholine-specific phospholipase C, leading to an accumulation of phosphocholine and diacylglycerol. This build-up can enhance the activity of FADS7_Degs1, which is involved in the synthesis of diacylglycerol into ceramides. | ||||||
D-erythro-Sphingosine | 123-78-4 | sc-3546 sc-3546A sc-3546B sc-3546C sc-3546D sc-3546E | 10 mg 25 mg 100 mg 1 g 5 g 10 g | $90.00 $194.00 $510.00 $2448.00 $9384.00 $15300.00 | 2 | |
Sphingosine is a sphingolipid that serves as a precursor for ceramide synthesis. Increased levels of sphingosine can enhance the activity of FADS7_Degs1, which converts sphingosine into ceramides. | ||||||
L-Serine | 56-45-1 | sc-397670 sc-397670A sc-397670B sc-397670C sc-397670D | 1 g 100 g 1 kg 5 kg 10 kg | $20.00 $133.00 $546.00 $1224.00 $2040.00 | ||
Serine is an amino acid involved in the synthesis of sphingolipids. Increased levels of serine can enhance the activity of FADS7_Degs1, which uses sphingolipids as substrates for ceramide synthesis. | ||||||