ER71 Activators
The chemical activators of ER71 are diverse, each influencing unique signaling pathways or cellular processes that indirectly enhance the functional activity of ER71. Androgens like Dihydrotestosterone (DHT) and estrogens such as Estradiol modulate ER71 activity through their receptor pathways, impacting sex-specific development and reproductive functions. Lithium Chloride and BIO (6-Bromoindirubin-3'-oxime), through the activation of Wnt signaling, can indirectly enhance ER71 activity in developmental processes and cell proliferation. Retinoic Acid, by modulating retinoic acid receptor signaling, potentially affects embryonic development pathways involving ER71. Additionally, Forskolin, by increasing cAMP levels, influences cellular processes that could impact ER71-regulated pathways.
Compounds like 5-Azacytidine and Trichostatin A, which modulate epigenetic mechanisms, can enhance ER71 activity by influencing gene expression patterns. Y-27632, a ROCK inhibitor, affects cytoskeletal dynamics, potentially impacting ER71 activity in cell movement and structural pathways. SB431542, by modulating TGF-β signaling, and PD98059, through its effects on the MAPK/ERK pathway, can influence ER71 activity in cell differentiation and development. Lastly, Rapamycin, as an mTOR inhibitor, can indirectly enhance ER71 activity in pathways related to cell growth and angiogenesis. These chemical activators, through their targeted actions on various signaling pathways and cellular processes, collectively contribute to the enhanced functionality of ER71 in a range of biological contexts.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $63.00 $182.00 | 8 | |
Estradiol, an estrogen, potentially enhances ER71 activity in reproductive tissue development and function by influencing estrogen receptor pathways that may interact with or modulate ER71. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium Chloride can activate Wnt signaling, which is involved in various developmental processes. Activation of Wnt signaling can indirectly enhance ER71 activity in pathways related to embryonic development and cell differentiation. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic Acid, involved in embryonic development, can enhance ER71 activity by influencing retinoic acid receptor signaling, potentially affecting pathways that involve ER71. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin activates adenylyl cyclase, increasing cAMP levels. This can enhance ER71 activity by modulating cellular processes that are cAMP-dependent, potentially affecting ER71-regulated pathways. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
Y-27632, a ROCK inhibitor, can influence cytoskeletal dynamics and cellular morphology. This may enhance ER71 activity in pathways related to cell movement and structure. | ||||||
GSK-3 Inhibitor IX | 667463-62-9 | sc-202634 sc-202634A sc-202634B | 1 mg 10 mg 50 mg | $58.00 $188.00 $884.00 | 10 | |
BIO is a GSK-3 inhibitor and can activate Wnt signaling. This may enhance ER71 activity in developmental pathways and processes like cell proliferation. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
PD98059 is an MEK inhibitor, which can modulate MAPK/ERK pathway, potentially influencing ER71 activity in pathways related to cell growth and differentiation. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
Trichostatin A, a histone deacetylase inhibitor, can influence chromatin structure and gene expression, potentially enhancing ER71 activity by modifying the expression of genes in ER71-related pathways. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin, an mTOR inhibitor, can affect cellular growth and metabolism. This may indirectly enhance ER71 activity in pathways related to cell growth and angiogenesis. | ||||||