Epac Activators
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Adenosine 3′,5′-cyclic monophosphate sodium salt monohydrate | 37839-81-9 | sc-291840 sc-291840A sc-291840B sc-291840C | 25 mg 100 mg 500 mg 1 g | $56.00 $92.00 $270.00 $398.00 | ||
Adenosine 3′,5′-cyclic monophosphate sodium salt monohydrate functions as a crucial second messenger, engaging in specific molecular interactions that activate exchange proteins directly stimulated by cAMP (EPAC). This compound facilitates distinct signaling pathways by promoting the exchange of GDP for GTP on small GTPases, thereby influencing cellular responses. Its hydrophilic nature enhances solubility, allowing for efficient diffusion across cellular membranes and rapid modulation of intracellular signaling dynamics. | ||||||
8-pCPT-2′-O-Me-cAMP | 634207-53-7 | sc-257020 | 1 mg | $306.00 | 5 | |
This is a cAMP analog designed to selectively activate EPAC over PKA (protein kinase A). | ||||||
(S)-Adenosine, cyclic 3′,5′-(hydrogenphosphorothioate) triethylammonium | 71774-13-5 | sc-202907 sc-202907A | 1 mg 5 mg | $107.00 $573.00 | ||
(S)-Adenosine, cyclic 3',5'-(hydrogenphosphorothioate) triethylammonium acts as a potent modulator of intracellular signaling through its role as an EPAC activator. This compound uniquely engages with specific GTP-binding proteins, promoting conformational changes that enhance their activity. Its triethylammonium group contributes to its solubility and stability in aqueous environments, facilitating rapid cellular uptake and effective downstream signaling cascades. The compound's distinct phosphorothioate modification also influences its reactivity and interaction with target proteins, providing a unique mechanism of action in cellular communication. | ||||||
Sp-Adenosine 3′,5′-cyclic monophosphorothioate triethylammonium salt | 93602-66-5 | sc-258176 | 1 mg | $143.00 | ||
Sp-Adenosine 3',5'-cyclic monophosphorothioate triethylammonium salt serves as a selective EPAC activator, influencing cAMP-mediated signaling pathways. Its unique phosphorothioate structure enhances binding affinity to target proteins, altering their functional dynamics. The triethylammonium moiety improves solubility, allowing for efficient cellular penetration. This compound's ability to modulate protein interactions and downstream effects underscores its significance in regulating cellular responses and signaling networks. | ||||||
Adenosine 3′,5′-cyclic Monophosphorothioate,8-Bromo-, Sp-Isomer,Sodium Salt | sc-221215 | 5 µmol | $390.00 | |||
Adenosine 3′,5′-cyclic Monophosphorothioate, 8-Bromo-, Sp-Isomer, Sodium Salt acts as a potent EPAC activator, engaging in specific molecular interactions that modulate intracellular signaling cascades. The presence of the bromine substituent introduces unique steric effects, influencing the compound's reactivity and selectivity towards target proteins. Its sodium salt form enhances stability and solubility, facilitating effective cellular uptake and promoting distinct kinetic profiles in signaling modulation. | ||||||
8-(6-Aminohexyl)aminoadenosine 3′:5′-cyclic monophosphate | 39824-30-1 | sc-214411 | 25 mg | $390.00 | ||
Another cAMP analog, this compound can selectively activate EPAC over PKA under specific conditions. | ||||||
8-CPT-cAMP | 93882-12-3 | sc-201569 sc-201569A | 20 mg 100 mg | $87.00 $316.00 | 19 | |
While it has the potential to activate both EPAC and PKA, in certain experimental settings, it can be utilized more for EPAC activation. | ||||||