Elm1 Activators
Elm1, or ELM1 kinase, is a serine/threonine protein kinase that plays a crucial role in a variety of cellular processes. It is best characterized in yeast (Saccharomyces cerevisiae), where it has been shown to be integral to cell cycle regulation, particularly in the progression through the G2/M phase. Elm1 is involved in the regulation of cytokinesis, the process of cell division, and septin organization, which is essential for maintaining cell structure and function.
In addition to its role in cell division, Elm1 is implicated in the regulation of cellular morphology. It interacts with and regulates other kinases and proteins involved in morphogenesis, helping to orchestrate the complex series of events that determine cell shape and structure. Elm1 also contributes to the cellular response to stress, participating in pathways that respond to various environmental and intracellular stimuli.Due to its involvement in fundamental cellular activities, dysregulation of Elm1 can have significant implications. For instance, abnormalities in cell cycle progression and cytokinesis can lead to genomic instability, a characteristic of many cancerous cells.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Hydroxyurea | 127-07-1 | sc-29061 sc-29061A | 5 g 25 g | $78.00 $260.00 | 18 | |
Hydroxyurea, known to induce DNA damage response, might upregulate Elm1 expression as part of the cellular stress response. | ||||||
Cisplatin | 15663-27-1 | sc-200896 sc-200896A | 100 mg 500 mg | $138.00 $380.00 | 101 | |
Cisplatin could enhance Elm1 expression through its role in DNA damage and the subsequent cellular repair mechanisms. | ||||||
Doxorubicin | 23214-92-8 | sc-280681 sc-280681A | 1 mg 5 mg | $176.00 $426.00 | 43 | |
Doxorubicin, a chemotherapy agent, might induce Elm1 expression due to its DNA-damaging effects, triggering stress response pathways. | ||||||
Etoposide (VP-16) | 33419-42-0 | sc-3512B sc-3512 sc-3512A | 10 mg 100 mg 500 mg | $51.00 $231.00 $523.00 | 63 | |
Etoposide, which causes DNA strand breaks, could potentially upregulate Elm1 as part of the DNA damage response. | ||||||
Camptothecin | 7689-03-4 | sc-200871 sc-200871A sc-200871B | 50 mg 250 mg 100 mg | $58.00 $186.00 $94.00 | 21 | |
Camptothecin, known for its role in inhibiting DNA replication, might influence Elm1 expression through cellular stress pathways. | ||||||
Bleomycin | 11056-06-7 | sc-507293 | 5 mg | $275.00 | 5 | |
Bleomycin, causing oxidative damage to DNA, could enhance Elm1 expression as a part of the cellular response to DNA damage. | ||||||
Hydrogen Peroxide | 7722-84-1 | sc-203336 sc-203336A sc-203336B | 100 ml 500 ml 3.8 L | $31.00 $61.00 $95.00 | 28 | |
H2O2, as an inducer of oxidative stress, may influence Elm1 expression by triggering cellular antioxidant responses. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $136.00 $446.00 | 114 | |
Thapsigargin, which induces endoplasmic reticulum stress, could potentially affect Elm1 expression as part of the unfolded protein response. | ||||||
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $172.00 $305.00 | 66 | |
Tunicamycin may upregulate Elm1 expression by inducing endoplasmic reticulum stress and the unfolded protein response. | ||||||