Date published: 2026-2-15

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EG434219 Inhibitors

EG434219 inhibitors are a class of chemical compounds specifically designed to target and inhibit the activity of the molecule EG434219, which is likely involved in key regulatory processes within cellular signaling or enzymatic pathways. EG434219 is presumed to play a critical role in modulating biochemical interactions or protein functions that are essential for maintaining cellular homeostasis. This molecule may be engaged in processes such as protein phosphorylation, dephosphorylation, or signal transduction, serving as a regulatory checkpoint in various cellular networks. Inhibition of EG434219 interferes with its ability to interact with target substrates or signaling molecules, thereby altering the biological pathways it regulates. These inhibitors provide a valuable tool for exploring the precise role of EG434219 in cellular processes and its impact on the broader biochemical landscape.

Structurally, EG434219 inhibitors are designed to bind to specific functional sites on the EG434219 molecule, such as its active site or allosteric sites that are crucial for its activity. These inhibitors may function through competitive inhibition, where they directly block the interaction between EG434219 and its substrates, or through non-competitive mechanisms that induce conformational changes, reducing the molecule's functional capabilities. By inhibiting EG434219, researchers can study the downstream effects on cellular pathways that rely on its activity, providing insights into how this molecule controls processes like protein-protein interactions, signal transduction, or metabolic regulation. This research helps to illuminate the role of EG434219 in maintaining cellular organization, contributing to the broader understanding of how regulatory molecules modulate complex biological systems and ensure proper cellular function.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

BAY 11-7082

19542-67-7sc-200615B
sc-200615
sc-200615A
5 mg
10 mg
50 mg
$62.00
$85.00
$356.00
155
(1)

Inhibits NF-kappaB signaling by preventing I-kappaB kinase activation, thereby downregulating Trim30c-mediated positive regulation of I-kappaB kinase/NF-kappaB signaling.

MG-132 [Z-Leu- Leu-Leu-CHO]

133407-82-6sc-201270
sc-201270A
sc-201270B
5 mg
25 mg
100 mg
$60.00
$265.00
$1000.00
163
(3)

Proteasome inhibitor blocking ubiquitin-proteasome-dependent degradation, disrupting Trim30c's ubiquitin protein ligase activity and stabilizing proteins involved in NF-kappaB signaling pathways.

NFκB Activation Inhibitor II, JSH-23

749886-87-1sc-222061
sc-222061C
sc-222061A
sc-222061B
5 mg
10 mg
50 mg
100 mg
$214.00
$257.00
$1775.00
$2003.00
34
(1)

Selectively inhibits nuclear translocation of NF-kappaB, counteracting Trim30c-mediated positive regulation of NF-kappaB transcription factor activity.

Celastrol, Celastrus scandens

34157-83-0sc-202534
10 mg
$158.00
6
(1)

Modulates multiple cellular pathways, including NF-kappaB signaling, indirectly inhibiting Trim30c's role in positive regulation of I-kappaB kinase/NF-kappaB signaling.

ML 120B Dihydrochloride

783348-36-7 (free base)sc-487759
5 mg
$380.00
(0)

Inhibits TAK1, a kinase in the NF-kappaB pathway, leading to reduced NF-kappaB signaling and countering Trim30c's positive regulation of I-kappaB kinase/NF-kappaB signaling.

Wedelolactone

524-12-9sc-200648
sc-200648A
1 mg
5 mg
$110.00
$337.00
8
(0)

Blocks IkappaB kinase activity, inhibiting NF-kappaB signaling and mitigating Trim30c's positive regulation of I-kappaB kinase/NF-kappaB signaling.

Embelin

550-24-3sc-201555
sc-201555A
10 mg
50 mg
$89.00
$339.00
5
(2)

Selectively inhibits XIAP, disrupting the inhibition of caspases and inducing apoptosis, potentially affecting Trim30c-mediated regulation of NF-kappaB signaling.

Parthenolide

20554-84-1sc-3523
sc-3523A
50 mg
250 mg
$81.00
$306.00
32
(2)

Inhibits IkappaB kinase and NF-kappaB activation, reducing Trim30c's positive regulation of I-kappaB kinase/NF-kappaB signaling.

Bortezomib

179324-69-7sc-217785
sc-217785A
2.5 mg
25 mg
$135.00
$1085.00
115
(2)

Proteasome inhibitor preventing degradation of IkappaB, leading to reduced NF-kappaB signaling and counteracting Trim30c-mediated positive regulation of I-kappaB kinase/NF-kappaB signaling.

IKK-2 Inhibitor IV

507475-17-4sc-203083
500 µg
$133.00
12
(1)

Inhibits IKK-2, a key component of NF-kappaB signaling, attenuating Trim30c's positive regulation of I-kappaB kinase/NF-kappaB signaling.