EG243866 Activators
Meiosin emerges as a pivotal gene orchestrating the initiation of meiosis and contributing significantly to cellular processes related to gamete generation within the nucleus. Predicted to enable DNA binding activity and protein dimerization, Meiosin's fundamental role lies in the activation of meiosis, the cellular response to retinoic acid, and the regulation of gamete generation. Located in the nucleus and expressed in the genitourinary system, Meiosin exhibits orthology to the human MEIOSIN, further underscoring its evolutionary significance in reproductive processes.
Activation of Meiosin involves a complex interplay of biochemical processes that intricately modulate its expression and functions. Direct activators impact Meiosin by influencing histone acetylation and deacetylation processes, providing a direct mechanism for the initiation of meiosis and the enhancement of gamete generation within the nucleus. Additionally, indirect activators target signaling pathways such as Wnt, MAPK/ERK, TGF-β, and PI3K, influencing Meiosin up-regulation and contributing to the overall activation process. This intricate network of signaling cascades highlights Meiosin's responsiveness to various cellular cues, emphasizing its central role in governing key events related to meiotic initiation and reproductive processes. The location of Meiosin in the nucleus and its expression in the genitourinary system further accentuate its significance in reproductive biology, where it likely plays a crucial role in ensuring the accurate execution of meiosis and the generation of functional gametes. The intricate regulation of Meiosin reflects its evolutionary conservation and essential contribution to cellular processes crucial for the perpetuation of genetic material.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Sodium Butyrate acts as a direct activator of Meiosin by influencing the histone acetylation process. It up-regulates Meiosin expression, stimulating the initiation of meiosis and enhancing gamete generation within the nucleus. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic Acid serves as a direct activator by binding to Meiosin, initiating meiosis. It directly influences the cellular response to retinoic acid, promoting the activation of Meiosin and facilitating key processes in gamete generation within the nucleus. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $87.00 | 9 | |
Valproic Acid acts as a direct activator by modulating histone deacetylation. It enhances Meiosin expression, promoting the activation of meiosis and facilitating gamete generation within the nucleus, emphasizing its role in the genitourinary system. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium Chloride serves as an indirect activator by influencing the Wnt signaling pathway. It up-regulates Meiosin, stimulating the initiation of meiosis and enhancing gamete generation within the nucleus, emphasizing its role in the genitourinary system. | ||||||
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $82.00 $216.00 $416.00 | 48 | |
SB431542 acts as an indirect activator by inhibiting the TGF-β signaling pathway. It up-regulates Meiosin, triggering the initiation of meiosis and promoting gamete generation within the nucleus of the genitourinary system, highlighting its role in the activation process. | ||||||
N6-Cyclopentyladenosine | 41552-82-3 | sc-204117 | 50 mg | $120.00 | 2 | |
N6-Cyclopentyladenosine indirectly activates Meiosin by binding to A1 adenosine receptors, inhibiting cAMP production. This leads to the up-regulation of Meiosin, initiating meiosis and enhancing gamete generation within the nucleus of the genitourinary system. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
Trichostatin A serves as a direct activator by inhibiting histone deacetylases. It enhances Meiosin expression, stimulating the initiation of meiosis and promoting gamete generation within the nucleus, emphasizing its role in the genitourinary system. | ||||||
GW 5074 | 220904-83-6 | sc-200639 sc-200639A | 5 mg 25 mg | $106.00 $417.00 | 10 | |
GW5074 acts as an indirect activator by inhibiting the MEK/ERK pathway. It up-regulates Meiosin, triggering the initiation of meiosis and promoting gamete generation within the nucleus of the genitourinary system, highlighting its role in the activation process. | ||||||