Molecular structure of N6-Cyclopentyladenosine, CAS Number: 41552-82-3
N6-Cyclopentyladenosine (CAS 41552-82-3)
See product citations (2)
Application:
N6-Cyclopentyladenosine is a selective Adenosine A1-R agonist
CAS Number:
41552-82-3
Purity:
>99%
Molecular Weight:
335.36
Molecular Formula:
C15H21N5O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
N6-Cyclopentyladenosine is a potent and selective A1 adenosine receptor agonist (Ki values are 2.3, 790 and 43 nM for human A1, A2A and A3 receptors respectively; EC50 = 18600 nM for HA2B).
N6-Cyclopentyladenosine (CAS 41552-82-3) References
- Adenosine receptors and their ligands. | Klotz, KN. 2000. Naunyn Schmiedebergs Arch Pharmacol. 362: 382-91. PMID: 11111832
- Therapeutic Potential of Highly Selective A3 Adenosine Receptor Ligands in the Central and Peripheral Nervous System. | Coppi, E., et al. 2022. Molecules. 27: PMID: 35335254
- Cancer-related somatic mutations alter adenosine A1 receptor pharmacology-A focus on mutations in the loops and C-terminus. | Wang, X., et al. 2022. FASEB J. 36: e22358. PMID: 35604751
- A1 and A2b adenosine receptors regulate GPX4 against ferroptosis of cardiomyocytes in myocardial infarction rat model and in vitro. | Zhang, W., et al. 2022. Tissue Cell. 77: 101828. PMID: 35653908
- Adenosine and astrocytes determine the developmental dynamics of spike timing-dependent plasticity in the somatosensory cortex. | Martínez-Gallego, I., et al. 2022. J Neurosci. 42: 6038-52. PMID: 35768208
- Normalized Theta but Increased Gamma Activity after Acetylcholinesterase Inhibitor Treatment in Alzheimer's Disease: Preliminary qEEG Study. | Fide, E., et al. 2022. Clin EEG Neurosci. 15500594221120723. PMID: 35957592
- Ex Vivo Feedback Control of Neurotransmission Using a Photocaged Adenosine A1 Receptor Agonist. | Craey, E., et al. 2022. Int J Mol Sci. 23: PMID: 36012151
- Adenosine as a Key Mediator of Neuronal Survival in Cerebral Ischemic Injury. | Khan, H., et al. 2022. Neurochem Res. 47: 3543-3555. PMID: 36042141
- The ADORA1 mutation linked to early-onset Parkinson's disease alters adenosine A1-A2A receptor heteromer formation and function. | Sarasola, LI., et al. 2022. Biomed Pharmacother. 156: 113896. PMID: 36279718
- Pannexin 1 activity in astroglia sets hippocampal neuronal network patterns. | Vasile, F., et al. 2022. PLoS Biol. 20: e3001891. PMID: 36477165
- Adenosine receptor stimulation inhibits methamphetamine-associated cue seeking. | Bachtell, RK., et al. 2023. J Psychopharmacol. 37: 192-203. PMID: 36629009
- Purinergic signaling: Diverse effects and therapeutic potential in cancer. | Kaur, J. and Dora, S. 2023. Front Oncol. 13: 1058371. PMID: 36741002
- Opioid-Induced Reductions in Amygdala Lateral Paracapsular GABA Neuron Circuit Activity. | Ronström, JW., et al. 2023. Int J Mol Sci. 24: PMID: 36768252
Activator of:
3BP1, Adenosine A1-R, Adenosine A3-R, calsyntenin-3, Cdc7, Contactin 1, EG243866, HEPACAM2, HuB, Katanin p80 BL1, KIF1A, Liprin α4, LOC622554, MPDU1, Neprilysin-2, Ott, PCDH2, PREP, PSM, Rim3, SLC17A2, and SPARCL1_Sc1.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
N6-Cyclopentyladenosine, 50 mg | sc-204117 | 50 mg | $120.00 |